Reversible Hypopituitarism with Pituitary Tuberculoma
2015; The Japanese Society of Internal Medicine; Volume: 54; Issue: 10 Linguagem: Inglês
10.2169/internalmedicine.54.3435
ISSN1349-7235
AutoresKeiji Tanimoto, Ayumi Imbe, Kanako Shishikura, Hisashi Imbe, Tetsuya Hiraiwa, Tomo Miyata, Naokado Ikeda, Toshihiko Kuroiwa, Jungo Terasaki, Toshiaki Hanafusa,
Tópico(s)Peripheral Neuropathies and Disorders
ResumoA 50-year-old woman presented with a headache and nausea. A sellar and suprasellar mass was detected on MRI; the tumor was heterogeneously enhanced with gadolinium, and the pituitary stalk was slightly thickened. Laboratory tests revealed severe growth hormone, luteinizing hormone, follicle-stimulating hormone and thyroid-stimulating hormone deficiencies. A pathological examination of the tumor showed scattered granulomas with central necrosis and Langhans giant cells. Tuberculin skin and QuantiFERON TB-Gold tests (QFT-2G) were positive. Accordingly, we diagnosed the patient with pituitary tuberculoma presenting with pituitary dysfunction. Following treatment with antituberculous drugs, the pituitary hormone function normalized and the pituitary tuberculoma disappeared.
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