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The Chameleon Within: Improving Antigen Delivery

1997; American Association for the Advancement of Science; Volume: 277; Issue: 5328 Linguagem: Inglês

10.1126/science.277.5328.910

1095-9203

James Madara,

Infant Nutrition and Health

Rare M cells found in the lining of the gut and lungs provide gateways for foreign substances to enter the body and be delivered to the immune system. In this issue of Science , KernA©is et al . describe a method of converting gut epithelial cells to M cells and begin to dissect the origins of the endogenous trigger for this process. Control of the flux of antigens across the gut lining would allow more efficient oral vaccination and immunization.