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MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae

1991; American Society for Microbiology; Volume: 173; Issue: 5 Linguagem: Inglês

10.1128/jb.173.5.1817-1820.1991

1098-5530

Qi Cheng, Corinne A. Michels,

Bacterial Genetics and Biotechnology

We have investigated the transport of maltose in a genetically defined maltose-fermenting strain of Saccharomyces cerevisiae carrying the MAL1 locus. Two kinetically different systems were identified: a high-affinity transporter with a Km of 4 mM and a low-affinity transporter with a Km of 70 to 80 mM. The high-affinity maltose transporter is maltose inducible and is encoded by the MAL11 (and/or MAL61) gene of the MAL1 (and/or MAL6) locus. The low-affinity maltose transporter is expressed constitutively and is not related to MAL11 and/or MAL61. Both maltose transporters are subject to glucose-induced inactivation.