Artigo Revisado por pares

Chronic Pyelonephritis at Autopsy

1967; American College of Physicians; Volume: 66; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-66-4-697

ISSN

1539-3704

Autores

Lawrence R. Freedman,

Tópico(s)

Urinary Bladder and Prostate Research

Resumo

Article1 April 1967Chronic Pyelonephritis at AutopsyLAWRENCE R. FREEDMAN, M.D.LAWRENCE R. FREEDMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-4-697 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAbout 6 years ago, an analysis of the frequency with which chronic pyelonephritis*was diagnosed at autopsy showed that males were affected about as frequently as females (2). These data were difficult to explain in view of the marked preponderance of clinical urinary infections in women. A subsequent study was conducted on an autopsy sample from a defined population in Japan. The rates of urinary infection were determined in the clinic and compared with the diagnosis of chronic pyelonephritis at autopsy. Once again, the frequency with which the diagnosis of chronic pyelonephritis was made in males exceeded that anticipated from...References1. FREEDMAN LR: Pyelonephritis and urinary tract infection, in Diseases of the Kidney, edited by STRAUSS, M. B., WELT, L. G. Little, Brown and Co., Boston, 1963, p. 469. Google Scholar2. KLEEMANFREEDMAN SELR: The finding of chronic pyelonephritis in males and females at autopsy. New Eng. J. Med. 263: 988, 1960. CrossrefMedlineGoogle Scholar3. FREEDMANPHAIRSEKIHAMILTONNEFZGER LRJPMHBMD: The epidemiology of urinary tract infections in Hiroshima. Yale J. Biol. Med. 37: 262, 1965. MedlineGoogle Scholar4. PAWLOWSKIBLOXDORFKIMMELSTIEL JMJWP: Chronic pyelonephritis: a morphologic and bacteriologic study. New Eng. J. Med. 268: 965, 1963. CrossrefMedlineGoogle Scholar5. MIALLKASSLINGSTUART WEEHJKL: Factors influencing arterial pressure in the general population in Jamaica. Brit. Med. J. 2: 497, 1962. CrossrefMedlineGoogle Scholar6. KUNINZACHAPAQUIN CMEAJ: Urinary-tract infections in school children. I. Prevalence of bacteriuria and associated urologic findings. New Eng. J. Med. 266: 1287, 1962. CrossrefMedlineGoogle Scholar7. PERKOFF GT: Genetics in renal disease, in Diseases of the Kidney, edited by STRAUSS, M. B., WELT, L. G. Little, Brown and Co., Boston, 1963, p. 901. Google Scholar8. DAWBORNFAIRLEYKINCAID-SMITHKING JKKFPWE: The association of peptic ulceration, chronic renal disease, and analgesic abuse. Quart. J. Med. 25: 69, 1966. Google Scholar9. MOSTOFIVERDER BRUEGGEDIGGS FKCFLW: Lesions in kidneys removed for unilateral hematuria in sickle-cell disease. Arch. Path. (Chicago) 63: 336, 1957. MedlineGoogle Scholar10. FREEDMAN LR: Inapparent diabetes mellitus as a cause of renal insufficiency due to Kimmelstiel-Wilson lesions. Bull. Hopkins Hosp. 100: 132, 1957. MedlineGoogle Scholar11. FREEDMAN LR: Experimental pyelonephritis. XII. Changes mimicking "chronic pyelonephritis" as a consequence of renal vascular occlusion in the rat. Yale J. Biol. Med. 39: 113, 1966. MedlineGoogle Scholar12. KIMMELSTIEL P: Case records of the Massachusetts General Hospital, Case No. 27-1966. New Eng. J. Med. 274: 1374, 1966. CrossrefGoogle Scholar13. KIMMELSTIEL P: Asymptomatic bacteriuria, a hypothetical concept, should be treated with caution, in Controversy in Internal Medicine, edited by INGELFINGER, F. J., RELMAN, A. S., FINLAND, M. W. B. Saunders Co., Philadelphia, 1966, p. 313. Google Scholar14. FREEDMANSEKIPHAIR LRMJP: The natural history and outcome of antibiotic treatment of urinary tract infections in women. Yale J. Biol. Med. 37: 245, 1965. MedlineGoogle Scholar15. PETERSDORF RG: Asymptomatic bacteriuria: a therapeutic enigma, in Controversy in Internal Medicine, edited by INGELFINGER, F. J., RELMAN, A. S., FINLAND, M. W. B. Saunders Co., Philadelphia, 1966, p. 302. Google Scholar16. BEESON PB: What is chronic pyelonephritis, in Progress in Pyelonephritis, edited by KASS, E. H. F. A. Davis Co., Philadelphia, 1965, p. 367. Google Scholar17. LIPMANTYRELLSMALLSHAPIRO RLEJAP: Evaluation of antibiotic therapy in acute pyelonephritis produced by Escherichia coli in rats. J. Lab. Clin. Med. 67: 546, 1966. Google Scholar18. KLEEMANHEWITTGUZE CRWLLB: Pyelonephritis. Medicine (Balt.) 39: 3, 1960. MedlineGoogle Scholar19. RELMAN AS: Some clinical aspects of chronic pyelonephritis, in Biology of Pyelonephritis (Henry Ford Hospital International Symposium), edited by QUINN, E. L., KASS, E. H. Little, Brown and Co., Boston, 1960, p. 355. Google Scholar20. LONGCOPEWINKENWERDER WTWL: Clinical features of the contracted kidney due to pyelonephritis. Bull. Hopkins Hosp. 53: 255, 1933. Google Scholar21. WEISSPARKER SF: Pyelonephritis: its relation to vascular lesions and to arterial hypertension. Medicine (Balt.) 18: 221, 1939. CrossrefGoogle Scholar22. MACAULAYSUTTON DRN: The prognosis of urinary infections in childhood. Lancet 2: 1318, 1957. CrossrefGoogle Scholar23. SAPHIRCOHEN ONA: Chronic pyelonephrilenta and the "malignant phase of hypertension." Arch. Intern. Med. (Chicago) 104: 748, 1959. CrossrefMedlineGoogle Scholar24. GINDER DR: Increased susceptibility of mice infected with mouse adenovirus to Escherichia coli-induced pyelonephritis. J. Exp. Med. 120: 1117, 1964. CrossrefMedlineGoogle Scholar25. ALDERMANFREEDMAN MHLR: Experimental pyelonephritis. X. The direct injection of E. coli protoplasts into the medulla of the rabbit kidney. Yale J. Biol. Med. 36: 157, 1963. MedlineGoogle Scholar26. BRAUDESIEMIENSKIJACOBS AIJI: Protoplast formation in human urine. Trans. Ass. Amer. Physicians 74: 234, 1961. MedlineGoogle Scholar27. GUTMANTURCKPETERSDORFWEDGWOOD LTMRGRJ: Significance of bacterial variants in urine of patients with chronic bacteriuria. J. Clin. Invest. 44: 1945, 1965. CrossrefMedlineGoogle Scholar28. GUZEKALMANSON LBGM: Observations on the host-parasite relationship in "protoplast" infection of the kidney, in Progress in Pyelonephritis, edited by KASS, E. H. F. A. Davis Co., Philadelphia, 1965, p. 229. Google Scholar29. PERKOFF GT: Hereditary chronic nephritis, in Disease of the Kidney, edited by STRAUSS, M. B., WELT, L. G. Little, Brown and Co., Boston, 1963, p. 953. Google Scholar30. GRUPECUPPAGEHEYMANN WEFEW: Congenital nephrotic syndrome with interstitial nephritis. Amer. J. Dis. Child. 111: 482, 1966. Google Scholar31. CLAIREAUXPEARSON AEMG: Chronic nephritis in a newborn infant. Arch. Dis. Child. 30: 366, 1955. CrossrefMedlineGoogle Scholar32. STRAUSS MB: Cystic disease of the renal medulla, in Diseases of the Kidney, edited by STRAUSS, M. B., WELT, L. G. Little, Brown and Co., Boston, 1963, p. 938. Google Scholar33. KERESZTURYMEGYERI SL: Histology of renal pyramids with special regard to changes due to ageing. Acta Morph. Acad. Sci. Hung. 11: 205, 1962. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New Haven, ConnecticutFrom the Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.This study was supported by career development award 6K3-HD-22,587, National Institute of Child Health and Human Development, and by research grant 4767, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.Requests for reprints should be addressed to Lawrence R. Freedman, M.D., Yale University School of Medicine, 333 Cedar St., New Haven, Conn. 06510.*Renal changes resulting from bacterial infection of the kidney (1).†The author is indebted to Dr. Averill Liebow for permission to examine the autopsy records and microscopic slides and to reproduce photographs of gross material. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEvidence-Informed Practice: Diagnostic Questions in Urinary Tract Infections in the ElderlyThe Paradigm Shift to Non-Treatment of Asymptomatic BacteriuriaUrinary Tract InfectionsPerspectives of a Long‐Time ObserverUrinary Tract InfectionsUrinary Tract InfectionsVesicoureteric Reflux and Renal InjuryUrinary Tract InfectionsUrinary tract infections in pregnancyNatural history of "lower" urinary tract infectionsPrevention of Renal Damage by Early Recognition of Urinary Tract Infections in ChildhoodDiagnostik und Therapie akuter und rezidivierender HarnwegsentzündungenThe Management of Urinary Tract InfectionsPathogenesis of PyelonephritisThe KidneyThe KidneyClinical Pyelonephritis and Focal Renal Scarring: A Selected Review of Pathogenesis, Prevention, and PrognosisThe Role of Urinary Tract Infection in Chronic Renal FailureImmunologie der Pyelonephritis — Beziehungen der Immunantwort zur PathogeneseDie chronische Pyelonephritis des ErwachsenenaltersInfection and papillary necrosisZur Wirksamkeit, Verträglichkeit und Pharmakokinetik von Sisomicin bei Nieren- und HarnwegsinfektionenUnilateral chronic pyelonephritis and hypertension: Coincidental or causal relationship?NephrologyThe Controversy of Treatment of Asymptomatic Bacteriuria in Non-Pregnant Women—ResolvedMaternal mortality rates in eclampsiaThe Bristol Pyelonephritis Registry: 10 Years OnLong-Term Therapy for Chronic Bacteriuria in Men U.S. Public Health Service Cooperative StudyRICHARD B. FREEMAN, M.D., F.A.C.P., W. McFATE SMITH, M.D., M.P.H., F.A.C.P., JAMES A. RICHARDSON, M.D., F.A.C.P., PATRICK J. HENNELLY, M.D., RICHARD H. THURM, M.D., F.A.C.P., CHRISTFRIED URNER, M.D., JOHN A. VAILLANCOURT, M.D., ROBERT J. GRIEP, M.D., F.A.C.P., LOUIS BROMERChronic Interstitial Nephritis: Etiologic FactorsT. MURRAY, M.D., M. GOLDBERG, M.D., F.A.C.P.Pyelonephritis: Pathogenesis and Unsolved ProblemsEPIDEMIOLOGY OF SYMPTOMATIC URINARY TRACT INFECTION IN CHILDHOODBacteriuria screening in a disease detection program for healthy femalesHost response in urinary tract infectionsPrimary and Secondary Renal Failure in a Total Community (Tecumseh, Michigan): Preponderance in the Elderly and Possible Antecedent Factors*THE INDWELLING URETHRAL CATHETER IN PATIENTS WITH ACUTE SPINAL CORD TRAUMABacterial Antigen in the KidneyUpper urinary tract in patients after traumatic spinal cord injuryEXPERIMENTAL PYELONEPHRITISActive Chronic Pyelonephritis without Evidence of Bacterial InfectionPYELONEPHRITIS-LIKE LESIONS AS A LATE EFFECT OF DIFFUSE INTRAVASCULAR COAGULATION 1 April 1967Volume 66, Issue 4Page: 697-710KeywordsAutopsyBacterial pathogensChild healthInfectious diseasesPathogenesisPediatric infectionsPyelonephritisRenal diseasesResearch grantsUrinary tract infections ePublished: 1 December 2008 Issue Published: 1 April 1967 PDF downloadLoading ...

Referência(s)