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Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

2008; IOS Press; Volume: 14; Issue: 2 Linguagem: Inglês

10.3233/jad-2008-14211

1875-8908

Joanna F. Collingwood, Ryan Chong, Takeshi Kasama, Lionel C. Gontard, Rafal E. Dunin‐Borkowski, George Perry, Mihály Pósfai, Sandra L. Siedlak, Edward T. Simpson, Mark A. Smith, Jon Dobson,

Alzheimer's disease research and treatments

Although it has been known for over 50 years that abnormal concentrations of iron are associated with virtually all neurodegenerative diseases, including Alzheimer's disease, its origin, nature and role have remained a mystery. Here, we use high-reso