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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Mutations Affecting Iron Transport in Escherichia coli

1970; American Society for Microbiology; Volume: 104; Issue: 1 Linguagem: Inglês

10.1128/jb.104.1.219-226.1970

ISSN

1098-5530

Autores

G B Cox, F. Gibson, Richard K.J. Luke, N. Newton, I.G. O'Brien, H. Rosenberg,

Tópico(s)

Metalloenzymes and iron-sulfur proteins

Resumo

A mutant of Escherichia coli K-12 unable to form an essential component of the enterochelin-dependent iron transport system has been isolated. This strain carries a mutation in a gene designated fep , mapping close to two genes, entA and entD , concerned with enterochelin synthesis. Strain AN102, which carries the fep − allele, accumulates large quantities of enterochelin and gives a growth response to sodium citrate. The cytochrome b 1 and total iron content, and the measurement of the uptake of 55 Fe 3+ , indicate an impairment of the enterochelin-dependent iron transport system. The growth response to sodium citrate is related to the presence, in strain AN102, of an inducible citrate-dependent iron transport system.

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