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Rhodiola plants: Chemistry and biological activity

2015; Elsevier BV; Volume: 23; Issue: 3 Linguagem: Inglês

10.1016/j.jfda.2015.04.007

2224-6614

Hsiu‐Mei Chiang, Hsin‐Chun Chen, Chin-Sheng Wu, Po‐Yuan Wu, Kuo‐Ching Wen,

Natural Antidiabetic Agents Studies

Rhodiola is a genus of medicinal plants that originated in Asia and Europe and are used traditionally as adaptogens, antidepressants, and anti-inflammatory remedies. Rhodiola plants are rich in polyphenols, and salidroside and tyrosol are the primary bioactive marker compounds in the standardized extracts of Rhodiola rosea. This review article summarizes the bioactivities, including adaptogenic, antifatigue, antidepressant, antioxidant, anti-inflammatory, antinoception, and anticancer activities, and the modulation of immune function of Rhodiola plants and its two constituents, as well as their potential to prevent cardiovascular, neuronal, liver, and skin disorders.