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The performance of a novel ball‐tipped Flush knife for endoscopic submucosal dissection: a case–control study

2010; Wiley; Volume: 32; Issue: 7 Linguagem: Inglês

10.1111/j.1365-2036.2010.04425.x

1365-2036

Takashi Toyonaga, M. Man-i, Tsuyoshi Fujita, Eisho Nishino, Wataru Ono, Yoshinori Morita, Tsuyoshi Sanuki, Atsuhiro Masuda, Masaru Yoshida, Hiromu Kutsumi, Hideto Inokuchi, Takeshi Azuma,

Metastasis and carcinoma case studies

Endoscopic submucosal dissection (ESD) using short needle knives is safe and effective, but bleeding is a problem due to low haemostatic capability.To assess the performance of a novel ball-tipped needle knife (Flush knife-BT) for ESD with particular emphasis on haemostasis.A case-control study to compare the performance for ESD of 30 pairs of consecutive early gastrointestinal lesions (oesophagus: 12, stomach: 32, colorectum: 16) with standard Flush knife (F) vs. Flush knife-BT (BT). Primary outcome was efficacy of intraprocedure haemostasis. Secondary outcomes included procedure time, procedure speed (dividing procedure time into the area of resected specimen), en bloc resection rate and recurrence rate.Median intraoperative bleeding points and bleeding points requiring haemostatic forceps were smaller in the BT group than in the F group (4 vs. 8, P < 0.0001, 0 vs. 3, P < 0.0001). There was no difference between groups for procedure time; however, procedure speed was shorter in the BT group (P = 0.0078). En bloc and en bloc R0 resection rates were 100%, with no perforation or post-operative bleeding. No recurrence was observed in either group at follow-up 1 year postprocedure.Ball-tipped Flush knife (Flush knife-BT) appears to improve haemostatic efficacy and dissection speed compared with standard Flush knife.