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Transcripts from an aberrantly re-arranged human T-cell receptor beta-chain gene.

1985; Springer Nature; Volume: 4; Issue: 5 Linguagem: Inglês

10.1002/j.1460-2075.1985.tb03762.x

1460-2075

Mary Collins, A. Maija Kissonerghis, M. J. Dunne, Cynthia J. Watson, Peter Rigby, Michael J. Owen,

Immune Cell Function and Interaction

Research Article1 May 1985free access Transcripts from an aberrantly re-arranged human T-cell receptor beta-chain gene. M.K. Collins M.K. Collins Search for more papers by this author A.M. Kissonerghis A.M. Kissonerghis Search for more papers by this author M.J. Dunne M.J. Dunne Search for more papers by this author C.J. Watson C.J. Watson Search for more papers by this author P.W. Rigby P.W. Rigby Search for more papers by this author M.J. Owen M.J. Owen Search for more papers by this author M.K. Collins M.K. Collins Search for more papers by this author A.M. Kissonerghis A.M. Kissonerghis Search for more papers by this author M.J. Dunne M.J. Dunne Search for more papers by this author C.J. Watson C.J. Watson Search for more papers by this author P.W. Rigby P.W. Rigby Search for more papers by this author M.J. Owen M.J. Owen Search for more papers by this author Author Information M.K. Collins, A.M. Kissonerghis, M.J. Dunne, C.J. Watson, P.W. Rigby and M.J. Owen The EMBO Journal (1985)4:1211-1215https://doi.org/10.1002/j.1460-2075.1985.tb03762.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info A number of cDNA clones homologous to the human T-cell receptor beta-chain gene have been isolated from a library constructed from the human leukaemic cell line Jurkat. The nucleotide sequences of two of these clones demonstrate that Jurkat synthesizes an RNA, probably derived from an aberrantly rearranged C beta 1 gene, which cannot encode a functional beta-chain. This transcript contains a novel joining region and similar transcripts appear to be relatively abundant in several T-cell lines. Previous ArticleNext Article Volume 4Issue 51 May 1985In this issue RelatedDetailsLoading ...