Artigo Acesso aberto Revisado por pares

Oral mucositis induced by anticancer treatments: physiopathology and treatments

2006; Dove Medical Press; Volume: 2; Issue: 2 Linguagem: Inglês

10.2147/tcrm.2006.2.2.159

ISSN

1178-203X

Autores

Lionel D’Hondt, Christophe Lonchay, Marc Andr�, Jean-Luc Canon,

Tópico(s)

Head and Neck Cancer Studies

Resumo

Oral mucositis is a frequent and devastating side effect of anticancer treatments. It impairs the patient's quality of life and also can be life threatening because severe infections and delayed or incomplete anticancer treatments may result. This problem has been largely overlooked and underestimated in the past. However, recently studies have been performed to precisely identify the epidemiology, cost, consequences, physiopathology, and treatments of oral mucositis. Clinical guidelines have recently been published to help the daily management of this frequent complication. In addition, some innovative new drugs, including palifermin, have been developed to prevent and treat this major side effect of cancer treatments. In this paper we summarize the recent developments of oral mucositis management.

Referência(s)