Treatment-Refractory Schizoaffective Disorder in a Patient with Dyke-Davidoff-Masson Syndrome
2009; Cambridge University Press; Volume: 14; Issue: 1 Linguagem: Inglês
10.1017/s1092852900020034
ISSN2165-6509
AutoresBenedikt L. Amann, Celia García de la Iglesia, Peter J. McKenna, Edith Pomarol‐Clotet, Marisa Sanchez-Guerra, Michael Orth,
Tópico(s)Protein Tyrosine Phosphatases
ResumoABSTRACT Dyke-Davidoff-Masson syndrome, or cerebral hemiatrophy, is a pre- or perinatally acquired entity characterized by predominantly neurologic symptoms, such as seizures, facial asymmetry, contralateral hemiplegia, and mental retardation. Psychiatric symptoms are rarely reported. We report the first case of left cerebral hemiatrophy and a late onset of treatment-resistant schizoaffective disorder after a stressful life event. The patient finally responded well to clozapine. The clinical history and results from structural neuroimaging are highlighted to discuss the possible developmental bias for psychotic disorders.
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