Artigo Revisado por pares

THE CURRENT PROBLEM OF STAPHYLOCOCCAL INFECTIONS

1956; American College of Physicians; Volume: 45; Issue: 5 Linguagem: Inglês

10.7326/0003-4819-45-5-748

ISSN

1539-3704

Autores

David E. Rogers,

Tópico(s)

RNA and protein synthesis mechanisms

Resumo

Article1 November 1956THE CURRENT PROBLEM OF STAPHYLOCOCCAL INFECTIONSDAVID E. ROGERS, M.D.DAVID E. ROGERS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-45-5-748 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the last decade staphylococcal infections have become a problem of increasing concern. Most of the acute bacterial infections of man respond promptly and predictably to the antimicrobial agents now available. Nevertheless, infections due to staphylococci have remained a serious therapeutic problem. It is generally believed that the incidence of staphylococcal infection has increased since the introduction of antimicrobials, although only a few studies to document this impression have appeared in the literature.9, 42, 64Despite the apparent close biologic relationship between staphylococci and other gram-positive cocci which produce acute human infections, there is increasing evidence to suggest that staphylococci...Bibliography1. BaldwinSylvesterShaffer JNRFTE: Personal communication. Google Scholar2. Barber M: Coagulase positive staphylococci resistant to penicillin, J. Path. and Bact. 59: 373, 1947. CrossrefGoogle Scholar3. Barber M: Staphylococcic infection due to penicillin-resistant strains, Brit. M. J. 2: 863, 1947. CrossrefMedlineGoogle Scholar4. BarberBurston MJ: Antibiotic resistant staphylococcal infection: a study of antibiotic sensitivity in relation to phage types, Lancet 2: 578, 1955. CrossrefGoogle Scholar5. BarberRozwadowska-Dowzenko MM: Infection by penicillin-resistant staphylococci, Lancet 2: 641, 1948. CrossrefMedlineGoogle Scholar6. BarnettMcKenney GDAC: Lactic acid in exudates and transudates, Proc. Soc. Exper. Biol. and Med. 23: 505, 1926. CrossrefGoogle Scholar7. BeigelmannRantz PMLA: The clinical importance of coagulase-positive penicillin resistant Staphylococcus aureus , New England J. Med. 242: 353, 1950. CrossrefMedlineGoogle Scholar8. BlairCarrBuckman JEMJ: Action of penicillin on staphylococci, J. Immunol. 52: 281, 1946. MedlineGoogle Scholar9. BlowersMasonWallaceWalton RGAKRM: Control of wound infection, Lancet 2: 786, 1955. CrossrefGoogle Scholar10. Boake WC: Antistaphylocoagulase in experimental staphylococcal infections, J. Immunol. 76: 89, 1956. MedlineGoogle Scholar11. BøeVogelsang JTM: Penicillin resistant pathogenic staphylococci isolated from the upper respiratory tract, Acta path. et microbiol. Scandinav. 26: 71, 1944. CrossrefGoogle Scholar12. BrysonDemerec VM: Bacterial resistance, Am. J. Med. 18: 723, 1955. CrossrefMedlineGoogle Scholar13. ChickeringParks HTJH: Staphylococcus aureus pneumonia, J. A. M. A. 72: 617, 1919. CrossrefGoogle Scholar14. ClarkeDalgleisnGillespie SKPGWA: Hospital cross infections with staphylococci resistant to several antibiotics, Lancet 1: 1132, 1952. CrossrefMedlineGoogle Scholar15. Collins HS: Personal communication. Google Scholar16. DearingHeilman WHFR: Micrococcic (staphylococcic) enteritis as a complication of antibiotic therapy: its response to erythromycin, Proc. Staff Meet., Mayo Clin. 28: 121, 1953. MedlineGoogle Scholar17. Demerec M: Production of staphylococcus strains resistant to various concentrations of penicillin, Proc. Nat. Acad. Sc. 31: 16, 1945. CrossrefMedlineGoogle Scholar18. DowlingLepperJackson HWMHGG: Observations on the epidemiological spread of antibiotic-resistant staphylococci with measurements of the changes in sensitivity to penicillin and Aureomycin, Am J. Pub. Health 43: 860, 1953. CrossrefGoogle Scholar19. Dubos RJ: Effect of ketone bodies and other metabolites on the survival and multiplication of staphylococci and tubercle bacilli, J. Exper. Med. 98: 145, 1953. CrossrefMedlineGoogle Scholar20. Dubos RJ: Biochemical determinants of microbial diseases, 1954, Harvard University Press, Cambridge, Massachusetts. Google Scholar21. DubosSchaedler RJRW: Reversible changes in the susceptibility of mice to bacterial infections. I. Changes brought about by injection of pertussis vaccine or of bacterial endotoxins, J. Exper. Med. 104: 53, 1956. CrossrefMedlineGoogle Scholar22. DuguidWallace JPAT: Air infection with dust liberated from clothing, Lancet 2: 845, 1948. CrossrefMedlineGoogle Scholar23. Ekstedt RD: The effect of coagulase on the antibacterial activity of normal human serum against selected strains of Micrococcus pyogenes , Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 119, 1956. CrossrefMedlineGoogle Scholar24. EkstedtNungester RDWJ: Coagulase in reversing antibacterial activity of normal human serum on Micrococcus pyogenes , Proc. Soc. Exper. Biol. and Med. 89: 90, 1955. CrossrefMedlineGoogle Scholar25. Elek SD: Experimental staphylococcal infections in the skin of man, Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 85, 1956. CrossrefMedlineGoogle Scholar26. ElekLevy SDE: Distribution of haemolysins in pathogenic and non-pathogenic staphylococci, J. Path. and Bact. 62: 541, 1950. CrossrefMedlineGoogle Scholar27. FinlandPetersonStrauss MOLE: Staphylococcal pneumonia occurring during an epidemic of influenza, Arch. Int. Med. 70: 183, 1942. CrossrefGoogle Scholar28. FinlandFrankWilcox MPFC: In vitro susceptibility of pathogenic staphylococci to 7 antibiotics (penicillin, streptomycin, bacitracin, polymyxin, aerosporin, Aureomycin, and Chloromycetin) with note on changing resistance of staphylococci to penicillin, Am. J. Clin. Path. 20: 325, 1950. CrossrefMedlineGoogle Scholar29. FinlandHaight MTH: Antibiotic resistance of pathogenic staphylococci: study of five hundred strains isolated at the Boston City Hospital from October, 1951 to February, 1952, Arch. Int. Med. 91: 143, 1953. CrossrefGoogle Scholar30. Fisher AM: The plasma coagulating properties of staphylococci, Bull. Johns Hopkins Hosp. 59: 393, 1936. Google Scholar31. FisherWagnerRoss AMHNRS: Staphylococcal endocarditis: some clinical and therapeutic observations on 38 cases, Arch. Int. Med. 95: 427, 1955. CrossrefGoogle Scholar32. Forbes GB: Diagnosis and management of severe infections in infants and children; review of experiences since introduction of sulfonamide therapy; staphylococcal empyema: importance of pyopneumothorax as complication, J. Pediat. 29: 45, 1946. CrossrefMedlineGoogle Scholar33. Forbes GB: Infection with penicillin resistant staphylococci in hospital and general practice, Brit. M. J. 2: 269, 1949. CrossrefGoogle Scholar34. Gallardo E: Sensitivity of bacteria from infected wounds to penicillin: results in 112 cases, War Med. 7: 100, 1945. Google Scholar35. GerheimFerguson EBJH: Staphylocoagulation in plasmas of various animal species, Proc. Soc. Exper. Biol. and Med. 71: 258, 1949. CrossrefMedlineGoogle Scholar36. Gladstone GP: The nutrition of Staphylococcus aureus: nitrogen requirements, Brit. J. Exper. Path. 22: 806, 1952. Google Scholar37. GouldMcKillop JCEJ: The carriage of Staphylococcus pyogenes var. aureus in the human nose, J. Hyg. 52: 304, 1954. CrossrefMedlineGoogle Scholar38. HaleSmith JHW: The influence of coagulase on the phagocytosis of staphylococci, Brit. J. Exper. Path. 26: 209, 1945. Google Scholar39. HallSpink WHWW: Penicillin therapy at the University hospitals, 1942-1944, Ann. Int. Med. 22: 510, 1945. LinkGoogle Scholar40. Helweg-LarsenHoffmeyerKielerThaysenThaysenThygesenWulff PHJEHJHPMH: Famine disease in German concentration camps, complications and sequels, with special reference to tuberculosis, mental disorders and social consequences, Acta psychiat. et neurol. Suppl. 83: 1952. Google Scholar41. HirshDowlingRobinson HLHFJA: Organisms resistant to penicillin obtained from patients, Arch. Int. Med. 82: 310, 1948. CrossrefGoogle Scholar42. Howe CW: Post-operative wound infections due to Staphylococcus aureus , New England J. Med. 251: 411, 1954. CrossrefMedlineGoogle Scholar43. Howe CW: Discussion of paper 15 in Conference on staphylococcal infections, Ann. New York Acad. Sc. 65: 189, 1956. Google Scholar44. Hughes WH: Failure of immunity responses in localized disease, Brit. M. J. 1: 366, 1945. CrossrefMedlineGoogle Scholar45. Hughes WH: The fibrin barrier regarded as a filter in inflammation, Brit. J. Exper. Path. 29: 173, 1948. MedlineGoogle Scholar46. KellawayMacCallumTebbutt CHPAH: Report of the Royal Commission of Inquiry into the fatalities at Bundaberg, in Parliamentary Papers of the Commonwealth of Australia, 1928, H. J. Green, Canberra. Google Scholar47. Kirby WM: Bacteriostatic and lytic actions of penicillin on sensitive and resistant staphylococci, J. Clin. Investigation 24: 165, 1945. CrossrefMedlineGoogle Scholar48. KleigerBlair BJE: Correlation between clinical and experimental findings in cases showing invasion of the blood stream by staphylococci, Surg., Gynec. and Obst. 71: 770, 1940. Google Scholar49. KnightCollins VHS: A current view on the problem of drug resistant staphylococci and staphylococcal infection, Bull. New York Acad. Med. 31: 549, 1955. MedlineGoogle Scholar50. KnightHolzer VAR: Studies on staphylococci from hospital patients. I. Predominance of strains of Group III phage patterns which are resistant to multiple antibiotics, J. Clin. Investigation 33: 1190, 1954. CrossrefMedlineGoogle Scholar51. LackWailling CHCG: A study of 435 strains of Staphylococcus pyogenes with reference to factors which may contribute to pathogenicity, J. Path. and Bact. 68: 431, 1954. CrossrefMedlineGoogle Scholar52. LeMaistre CA: Personal communication. Google Scholar53. LepperMoultonDowlingJacksonKofman MHBHFGGS: Epidemiology of erythromycin-resistant staphylococci in a hospital population: effect on therapeutic activity of erythromycin, in Antibiotics Annual, edited by Welch, H. and Marti-Ibanez, F., 1953, Medical Encyclopedia, Inc., New York, p. 308. Google Scholar54. Loeb L: The influence of certain bacteria on the coagulation of the blood, J. Med. Research 10: 407, 1903-1904. Google Scholar55. Mackaness GB: The action of drugs on intracellular tubercle bacilli, J. Path. and Bact. 64: 429, 1952. CrossrefMedlineGoogle Scholar56. MartinMcKinneyGreen SPGRR: Effect of glucose, fructose and insulin on the leukocytes of diabetics, J. Clin. Investigation 32: 586, 1953. CrossrefGoogle Scholar57. McCuneDineenBatten RMPAJC: The effect of antimicrobial drugs on an experimental staphylococcal infection in mice, Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 91, 1956. CrossrefMedlineGoogle Scholar58. McDermott W: The nature of the lesion and the response to antimicrobial therapy, in Evaluation of chemotherapeutic agents, 1949, edited by MacLeod, C. M., Columbia University Press, New York, p. 92. Google Scholar59. McGuinnessMusgrove FGGS: Epidemic of puerperal mastitis associated with nasopharyngeal and skin infection in newborn, Canad. M. A. J. 61: 356, 1949. MedlineGoogle Scholar60. Menkin V: Dynamics of inflammation, 1940, The Macmillan Co., New York, p. 78. Google Scholar61. Michael M: Staphylococcus aureus pneumonia, J. A. M. A. 118: 869, 1942. CrossrefGoogle Scholar62. PantonValentine PNFC: Staphylococcal toxin, Lancet 1: 506, 1932. CrossrefGoogle Scholar63. PhillipsRomanskyNasou LVMJJP: Staphylococcal septicemia and endocarditis secondary to cortisone-treated exfoliative dermatitis due to penicillin, in Antibiotics annual, 1955, edited by H. Welsh and F. Marti-Ibanez, Medical Encyclopedia, Inc., New York, p. 68. Google Scholar64. Prissick FH: Antibiotic-resistant staphylococci and related infections, Am. J. M. Sc. 225: 299, 1953. MedlineGoogle Scholar65. RammelkampBadgerDingleFellerHodges CHGFJMAERG: Antigenicity of cell-free staphylococcal coagulase, J. Infect. Dis. 86: 159, 1950. CrossrefMedlineGoogle Scholar66. RammelkampLebovitz CHJL: The role of coagulase in staphylococcal infections, Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 144, 1956. CrossrefMedlineGoogle Scholar67. RammelkampMaxon CHT: Resistance of Staphylococcus aureus to the action of penicillin, Proc. Soc. Exper. Biol. and Med. 51: 386, 1942. CrossrefGoogle Scholar68. ReesShooterShawe EGRAGD: Sensitivity to five antibiotics of a further 200 strains of Staphylococcus pyogenes isolated from out-patients, Lancet 1: 1409, 1955. Google Scholar69. RobbinsTompsett WCR: Treatment of enterococcal endocarditis and bacteremia, Am. J. Med. 10: 278, 1951. CrossrefMedlineGoogle Scholar70. Rogers DE: Studies on bacteremia. I. Mechanisms relating to the persistence of bacteremia in rabbits following the intravenous injection of staphylococci, J. Exper. Med. 103: 713, 1956. CrossrefMedlineGoogle Scholar71. RogersTompsett DER: The survival of staphylococci within human leukocytes, J. Exper. Med. 95: 209, 1952. CrossrefMedlineGoogle Scholar72. Rogers HJ: The formation of extra-cellular enzymes by staphylococci, Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 132, 1956. CrossrefMedlineGoogle Scholar73. RountreeBarbour PMRG: Staphylococcus pyogenes in new-born babies in a maternity hospital, M. J. Australia 1: 525, 1950. CrossrefMedlineGoogle Scholar74. RountreeThompson PMEF: Incidence of antibiotic resistant staphylococci in a hospital, Lancet 2: 262, 1952. CrossrefMedlineGoogle Scholar75. ShafferKuceraSpink JMCJWW: The protection of intracellular brucella against therapeutic agents and the bactericidal action of serum, J. Exper. Med. 97: 77, 1953. CrossrefMedlineGoogle Scholar76. SkinnerKeefer DCS: Significance of bacteremia caused by Staphylococcus aureus: a study of 122 cases and a review of the literature concerned with experimental infection in animals, Arch. Int. Med. 68: 870, 1941. CrossrefGoogle Scholar77. SmithDubos JMRJ: The behavior of virulent and avirulent staphylococci in the tissues of normal mice, J. Exper. Med. 103: 87, 1956. CrossrefMedlineGoogle Scholar78. SmithDubos JMRJ: The effect of nutritional disturbances on the susceptibility of mice to staphylococcal infections, J. Exper. Med. 103: 109, 1956. CrossrefMedlineGoogle Scholar79. SmithDubos JMRJ: The effect of dinitrophenol and thyroxin on the susceptibility of mice to staphylococcal infections, J. Exper. Med. 103: 119, 1956. CrossrefMedlineGoogle Scholar80. SmithHale WJH: The nature and mode of action of staphylococcal coagulase, Brit. J. Exper. Path. 25: 101, 1944. Google Scholar81. SmithHaleSmith WJMM: The role of coagulase in staphylococcal infections, Brit. J. Exper. Path. 28: 57, 1947. MedlineGoogle Scholar82. Spink WW: Clinical and biologic significance of penicillin-resistant staphylococci including observations with streptomycin, Aureomycin, chloramphenicol, and Terramycin, J. Lab. and Clin. Med. 37: 278, 1951. MedlineGoogle Scholar83. Spink WW: Staphylococcal infections and the problem of antibiotic resistant staphylococci, Arch. Int. Med. 94: 167, 1954. CrossrefGoogle Scholar84. Spink WW: The clinical problem of antimicrobial resistant staphylococci, Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 175, 1956. CrossrefMedlineGoogle Scholar85. SpinkHallFerris WWWHV: Clinical significance of staphylococci with natural or acquired resistance to the sulfonamides and to penicillin, J. A. M. A. 128: 555, 1945. CrossrefGoogle Scholar86. Spittlehouse KE: Phage types of Staphylococcus pyogenes isolated from impetigo and sycosis barbae, Lancet 2: 378, 1955. CrossrefGoogle Scholar87. Summers GA: Penicillin-resistant staphylococci: distribution among out-patients, Lancet 1: 135, 1952. CrossrefMedlineGoogle Scholar88. TagerHales MHB: Experimental production of antibodies to staphylocoagulase, J. Immunol. 60: 475, 1948. MedlineGoogle Scholar89. Tager M: Problems in the coagulation of plasma by staphylocoagulase, Ann. New York Acad. Sc. (Conference on staphylococcal infections) 65: 109, 1956. CrossrefMedlineGoogle Scholar90. TagerHales MHB: Studies on coagulase-reacting factor; properties of coagulase-reacting factor, and relation to blood clotting components, J. Immunol. 60: 1, 1948. MedlineGoogle Scholar91. Tompsett R: The survival of staphylococci within phagocytic cells, Bull. New York Acad. Med. 30: 480, 1954. Google Scholar92. Valentine FC: Further observations on the role of toxin in staphylococcal infections, Lancet 1: 526, 1936. CrossrefGoogle Scholar93. Vogelsang TM: Incidence of penicillin-resistant pathogenic staphylococci isolated from the upper respiratory tract of young healthy persons, Acta path. et microbiol. Scandinav. 29: 363, 1951. CrossrefMedlineGoogle Scholar94. VourekaHughes AWH: Frequency of penicillin resistant staphylococci, Brit. M. J. 1: 395, 1949. CrossrefMedlineGoogle Scholar95. Walston HD: The clotting of plasma through staphylococci and their products, J. Hyg. 35: 549, 1935. MedlineGoogle Scholar96. WilsonCockroft RWM: The problem of penicillin resistant staphylococcal infection, Canad. M. A. J. 66: 548, 1952. MedlineGoogle Scholar97. WoodBennettYardley JSILJH: Staphylococcal enterocolitis in chinchillas, Bull. Johns Hopkins Hosp. 98: 454, 1956. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Presented as a Morning Lecture at the Thirty-seventh Annual Session of The American College of Physicians, Los Angeles, California, April 20, 1956.From the Department of Medicine, New York Hospital-Cornell University Medical College.†Lowell M. Palmer Senior Fellow in Medicine.A portion of the studies reported in this paper was supported by grants from Charles Pfizer, Brooklyn, N. Y., Lederle Laboratories, Pearl River, N. Y., and The Upjohn Company, Kalamazoo, Michigan.Requests for reprints should be addressed to David E. Rogers, M.D., The New York Hospital, 525 East Sixty-eighth Street, New York-21, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA New-Class Antibacterial—Almost. 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