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BIBTEX RIS

A dendritic β-galactosidase-responsive folate–monomethylauristatin E conjugate

2015; Royal Society of Chemistry; Volume: 51; Issue: 87 Linguagem: Inglês

10.1039/c5cc05294g

ISSN

1364-548X

Autores

Jérôme Alsarraf, Elodie Péraudeau, Pauline Poinot, Isabelle Tranoy‐Opalinski, Jonathan Clarhaut, Brigitte Renoux, Sébastien Papot,

Tópico(s)

HIV/AIDS drug development and treatment

Resumo

We designed a dendritic folate–drug conjugate allowing the β-galactosidase-catalysed release of two MMAE molecules inside folate receptor-positive cancer cells.

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