Revisão Revisado por pares

Evaluation and Management of the Adolescent Varicocele

2015; Lippincott Williams & Wilkins; Volume: 194; Issue: 5 Linguagem: Inglês

10.1016/j.juro.2015.06.079

ISSN

1527-3792

Autores

Thomas F. Kolon,

Tópico(s)

Sexual Differentiation and Disorders

Resumo

No AccessJournal of UrologyReview Article1 Nov 2015Evaluation and Management of the Adolescent Varicocele Thomas F. Kolon Thomas F. KolonThomas F. Kolon View All Author Informationhttps://doi.org/10.1016/j.juro.2015.06.079AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Varicocele is one of the most common genital conditions referred to pediatric urologists. Most adolescents with varicocele are asymptomatic and their fertility future (and surgery benefit) is largely unknown. This review assesses varicocele evaluation, management and indications for repair, as well as types and success of varicocelectomy. Materials and Methods: A systematic literature review was performed on Embase™, PubMed® and Google Scholar™ for adolescent varicocele. Original research articles and relevant reviews were examined, and a synopsis of these data was generated for a comprehensive review of clinical adolescent varicocele management. Results: The prevalence of adolescent varicocele is similar to the adult population. While ultrasound is the most sensitive method for determining testicular volumes, orchidometer measurement may be adequate to gauge significant discordance. Significant hypotrophy of the affected testis with poor total testicular volume may indicate a testis at risk and warrant surgical repair. Similar findings have been noted with an associated high peak retrograde venous flow. Testicular hypotrophy often resolves following surgery but may also improve spontaneously if followed through adolescence. Continued scrotal pain despite adequate support or serial abnormal semen analysis in Tanner stage V boys is an indication for varicocelectomy. Artery and lymphatic sparing techniques (microscopic subinguinal or laparoscopic) are associated with the lowest risk of recurrence and complications. Conclusions: Overtreatment and under treatment are medically and financially costly. Abnormal serial semen analysis with or without testicular hypotrophy is an indication for varicocele repair. If observation remains the treatment, followup with an adult urologist should be encouraged until paternity is achieved. References 1 : The prevalence of varicocele and varicocele-related testicular atrophy in Turkish children and adolescents. BJU Int2000; 86: 490. Google Scholar 2 : The adolescent varicocele: what's new with an old problem in young patients?. Pediatrics1997; 100: 112. Crossref, Medline, Google Scholar 3 : Varicocele in adolescence induces left and right testicular volume loss. BJU Int2001; 87: 499. Google Scholar 4 : Testicular hypotrophy does not correlate with grade of adolescent varicocele. J Urol2005; 174: 2367. Link, Google Scholar 5 : Relationship of varicocele grade and testicular hypotrophy to semen parameters in adolescents. J Urol2007; 178: 1584. Link, Google Scholar 6 : Prevention of fertility disorders by detection and treatment of varicocele at school and college age. Andrologia1976; 8: 47. Google Scholar 7 : Transient asynchronous testicular growth in adolescent males with a varicocele. J Urol2008; 180: 1111. Link, Google Scholar 8 : Reversal of testicular growth failure by varicocele ligation. J Urol1987; 137: 475. Link, Google Scholar 9 : Progressive testicular atrophy in the varicocele patient. J Urol1977; 117: 175. Link, Google Scholar 10 : Semen analysis in young men with varicocele: preliminary study. J Urol1996; 156: 788. Link, Google Scholar 11 : Effects of varicocelectomy on testis volume and semen parameters in adolescents: a randomized prospective study. Nagoya J Med Sci1995; 58: 127. Google Scholar 12 : Testicular growth arrest and adolescent varicocele: does varicocele size make a difference?. J Urol2002; 168: 1689. Link, Google Scholar 13 : Comparison of testicular volume differential calculations in adolescents with varicoceles. J Pediatr Urol2014; 10: 396. Google Scholar 14 : Testicular volume: comparison of orchidometer and US measurements in dogs. Radiology2002; 222: 114. Google Scholar 15 : Comparative assessment of pediatric testicular volume: orchidometer versus ultrasound. J Urol2000; 164: 1111. Link, Google Scholar 16 : Normative values for testicular volume measured by ultrasonography in a normal population from infancy to adolescence. Horm Res Paediatr2011; 76: 56. Google Scholar 17 : Variations in the management of asymptomatic adolescent grade 2 or 3 left varicoceles: a survey of practitioners. J Pediatr Urol2014; 10: 430. Google Scholar 18 : Diagnostic and management approaches to pediatric and adolescent varicocele: a survey of pediatric urologists. Urology2014; 84: 450. Google Scholar 19 : Loss of fertility in men with varicocele. Fertil Steril1993; 59: 613. Crossref, Medline, Google Scholar 20 : The adolescent varicocele I: left testicular hypertrophy following varicocelectomy. J Urol1999; 162: 1447. Link, Google Scholar 21 : Varicocele: a progressive or static lesion?. Urology1993; 42: 541. Google Scholar 22 : Adolescent varicocelectomy: postoperative catch-up growth is not secondary to lymphatic ligation. J Pediatr Urol2009; 5: 37. Google Scholar 23 : Adolescent varicocele—is the 20/38 harbinger a durable predictor of testicular asymmetry?. J Urol2013; 189: 1897. Link, Google Scholar 24 : Conservative management of adolescent varicoceles: a retrospective review. Urology2008; 72: 77. Google Scholar 25 : Dilemma of adolescent varicocele: long-term outcome in patients managed surgically and in patients managed expectantly. J Pediatr Urol2013; 9: 1018. Google Scholar 26 : Active surveillance of the adolescent with varicocele: predicting semen outcomes from ultrasound. J Urol2014; 191: 1401. Link, Google Scholar 27 : Pubertal screening and treatment for varicocele do not improve chance of paternity as adult. J Urol2013; 189: 2298. Link, Google Scholar 28 Kolon TF, Zderic SA, Shukla AR et al: Personal communication. Google Scholar 29 : Gonodotroph and Leydig cell responsiveness in the male rat. Effects of experimental left varicocele. J Androl1990; 11: 555. Google Scholar 30 : Histological findings in testes with varicocele during childhood and their therapeutic consequences. Eur J Pediatr1980; 133: 139. Google Scholar 31 : The chance for fertility in adolescent boys after corrective surgery for varicocele. J Urol1995; 154: 731. Link, Google Scholar 32 : Pituitary gonadal dysfunction in adolescents with varicocele. Urology1993; 42: 179. Google Scholar 33 : The adolescent varicocele: the crucial role of hormonal tests in selecting patients with testicular dysfunction. J Pediatr Surg2003; 38: 120. Google Scholar 34 : Altered serum inhibin B levels in adolescents with varicocele. J Pediatr Surg2007; 42: 390. Google Scholar 35 : Altered serum profile of inhibin B, Pro-alphaC and anti-Müllerian hormone in prepubertal and pubertal boys with varicocele. Clin Endocrinol (Oxf)2004; 60: 758. Google Scholar 36 : Report on varicocele and infertility. Fertil Steril2004; 82: S142. Google Scholar 37 : European Association of Urology Guidelines on Male Infertility: the 2012 update. Eur Urol2012; 62: 324. Google Scholar 38 : Sperm parameters after early left varicocele treatment. Fertil Steril1998; 69: 347. Google Scholar 39 : Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique. J Androl2009; 30: 33. Google Scholar 40 : Benefits of microsurgical repair of adolescent varicocele: comparison of semen parameters in fertile and infertile adults with varicocele. Urology2005; 65: 554. Google Scholar 41 : Review of current varicocelectomy techniques and their outcomes. BJU Int2011; 108: 1157. Google Scholar 42 : Beneficial effects of varicocele embolization on semen parameters. Basic Clin Androl2014; 24: 9. Google Scholar 43 : Long-term outcomes of adolescent varicoceles treated with selective gonadal vein embolization: 23 years' experience. J Urol2014; 191: e255. abstract MP26-11. Link, Google Scholar 44 : Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Fertil Steril2007; 88: 639. Google Scholar 45 : Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized clinical trials. Korean J Urol2013; 54: 703. Google Scholar 46 : Testicular growth and gonadotrophin response associated with varicocele repair in adolescent males. BJU Int2003; 91: 75. Google Scholar 47 : Hormonal parameters and testicular volume in children and adolescents with unilateral varicocele: preoperative and postoperative findings. J Urol1994; 152: 794. Abstract, Google Scholar 48 : The effect of varicocelectomy on serum testosterone levels in infertile men with varicoceles. J Urol1995; 154: 1752. Link, Google Scholar 49 : Effect of surgical repair on testosterone production in infertile men with varicocele: a meta-analysis. Int J Urol2012; 19: 149. Google Scholar 50 : Varicocelectomy is associated with increases in serum testosterone independent of clinical grade. Urology2013; 81: 1213. Google Scholar © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byNiederberger C (2018) Re: Introduction: Varicoceles: A Contemporary PerspectiveJournal of Urology, VOL. 199, NO. 6, (1381-1383), Online publication date: 1-Jun-2018.Çayan S, Şahin S and Akbay E (2017) Paternity Rates and Time to Conception in Adolescents with Varicocele Undergoing Microsurgical Varicocele Repair vs Observation Only: A Single Institution Experience with 408 PatientsJournal of Urology, VOL. 198, NO. 1, (195-201), Online publication date: 1-Jul-2017.Faasse M (2015) Re: Semen Parameters in Adolescents with Varicocele: Association with Testis Volume Differential and Total Testis VolumeJournal of Urology, VOL. 195, NO. 2, (527-528), Online publication date: 1-Feb-2016. Volume 194Issue 5November 2015Page: 1194-1201 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.Keywordsadolescenttestissemen analysisvaricoceleinfertilityMetricsAuthor Information Thomas F. Kolon More articles by this author Expand All Advertisement PDF downloadLoading ...

Referência(s)
Altmetric
PlumX