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Drug-Induced Tardive Dyskinesia

1981; Linguagem: Inglês

10.1007/978-94-011-8123-5_4

0097-8361

Hitoshi Itoh,

Epilepsy research and treatment

Drug-induced tardive dyskinesia, which occurs in the course of long-term administration of psychotropic drugs, especially neuroleptics, and persists for years even after drug removal, began to be reported in the late 1950s. Since then, more than 100 investigations on this subject have been described. And it is estimated that 10 to 30 percent of long-term hospitalized psychiatric patients in Europe and North America exhibit tardive dyskinesia, whereas 5 to 20 percent of patients exhibit this syndrome in Japan. These findings suggest that the manifestation of tardive dyskinesia will become a serious problem in the investigation of psychotropic drug treatment.