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AIDS-Associated Cerebral Toxoplasmosis: An Update on Diagnosis and Treatment

1996; Springer Science+Business Media; Linguagem: Inglês

10.1007/978-3-642-51014-4_19

2196-9965

Adriana Ammassari, Rita Murri, A. Cingolani, Andrea De Luca, Andrea Antinori,

Cytomegalovirus and herpesvirus research

Toxoplasmic encephalitis (TE) is one of the major opportunistic infections of the central nervous system (CNS) and the most frequent cause of focal brain lesions (FBL) in patients with acquired immunodeficiency syndrome (AIDS) (Luft et al. 1993). CNS toxoplasmosis is rapidly progressive and fatal without treatment and has been reported to be the AIDS index diagnosis in 22%-51% of patients infected with human immunodeficiency virus (HIV) (Leport et al. 1988; Cohn et al. 1989; Dannemann et al. 1991; Zangerle et al. 1991; Porter and Sande 1992).