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Cherubism: Case Report, Imaging Findings, and Review of the Literature

2015; Elsevier BV; Volume: 120; Issue: 2 Linguagem: Inglês

10.1016/j.oooo.2015.02.110

2212-4411

ISABELLE DA ROCHA CÂMARA, Fábio Wildson Gurgel Costa, Pedro Esau Macedo Machado, ADRIANO DUARTE QUITANS, JORGE ANTONIO DIAZ CASTRO,

Oral and Maxillofacial Pathology

Cherubism is an autosomal dominant hereditary bone disorder that is characterized by the painless expansion of the mandible and maxilla in children. The disease begins in childhood and progresses until adolescence, when it stabilizes and then subsides in adulthood. Cherubism can appear as an isolated case or in members of the same family. A 13-year-old male sought treatment in our department of oral and maxillofacial surgery for a bilateral expansion of the mandible, with facial symmetry, that had evolved over a 5 year-period. Clinical examination revealed a considerable bilateral increase in the volume of the mandibular body. Patient reported no paresthesia or painful symptoms. Radiography showed bilateral multilocular lesions in the mandibular body and ramus, with cortical involvement and the presence of unerupted teeth. After 3 years of follow-up, involution of the lesion was observed.