Lung uptake of Tc-99m sulfur colloid in liver and spleen imaging.
1978; National Institutes of Health; Volume: 19; Issue: 1 Linguagem: Inglês
Autores
William C. Klingensmith, S. L. Yang, H.N. Wagner,
Tópico(s)Pneumocystis jirovecii pneumonia detection and treatment
ResumoTwenty-seven patients with increased lung uptake of technetium-99m sulfur colloid (TcSC) were studied as a group and after classification by the degree of lung uptake (15 patients mild, 6 moderate, and 6 marked) to determine survival rate and the incidence of associated abnormalities. Using life-table data based on all 27 patients, it is estimated that 74 percent would be alive at 6 mo; this is significantly higher (p < 0.02) than the 38 percent survival estimate at 6 mo for patients reported in the literature. Twenty-two of the 27 patients (81 percent) had increased splenic uptake of TcSC, 15 (56 percent) had splenomegaly, 17 (63 percent) had an abnormal liver image (enlargement or nonhomogeneity), and 9 (33 percent) had increased bone-marrow uptake. As the degree of lung uptake increased, there was a tendency for the survival rate to decrease and for the incidence of other abnormalities in the liver and spleen images to increase. This tendency was statisticaly significant (p < 0.05) for abnormal liver image, and also for increased bone-marrow uptake and splenomegaly when patients with moderate and marked lung uptake were combined and compared with patients with mild lung uptake. Increased lung uptake of TcSC is strongly associatedmore » with other abnormalities in the liver and spleen images, but is not necessarily associated with a poor prognosis, particularly when the degree of increased lung uptake is mild.« less
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