Portal de Periódicos da CAPES

A novel class of plant proteins containing a homeodomain with a closely linked leucine zipper motif.

1991; Springer Nature; Volume: 10; Issue: 7 Linguagem: Inglês

10.1002/j.1460-2075.1991.tb07703.x

1460-2075

Ida Ruberti, Giovanna Sessa, Sara Lucchetti, Giorgio Morelli,

RNA and protein synthesis mechanisms

Research Article1 July 1991free access A novel class of plant proteins containing a homeodomain with a closely linked leucine zipper motif. I. Ruberti I. Ruberti Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author G. Sessa G. Sessa Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author S. Lucchetti S. Lucchetti Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author G. Morelli G. Morelli Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author I. Ruberti I. Ruberti Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author G. Sessa G. Sessa Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author S. Lucchetti S. Lucchetti Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author G. Morelli G. Morelli Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. Search for more papers by this author Author Information I. Ruberti1, G. Sessa1, S. Lucchetti1 and G. Morelli1 1Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy. The EMBO Journal (1991)10:1787-1791https://doi.org/10.1002/j.1460-2075.1991.tb07703.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The homeobox, a 183 bp DNA sequence element, was originally identified as a region of sequence similarity between many Drosophila homeotic genes. The homeobox codes for a DNA-binding motif known as the homeodomain. Homeobox genes have been found in many animal species, including sea urchins, nematodes, frogs, mice and humans. To isolate homeobox-containing sequences from the plant Arabidopsis thaliana, a cDNA library was screened with a highly degenerate oligonucleotide corresponding to a conserved eight amino acid sequence from the helix-3 region of the homeodomain. Using this strategy two cDNA clones sharing homeobox-related sequences were identified. Interestingly, both of the cDNAs also contain a second element that potentially codes for a leucine zipper motif which is located immediately 3′ to the homeobox. The close proximity of these two domains suggests that the homeodomain-leucine zipper motif could, via dimerization of the leucine zippers, recognize dyad-symmetrical DNA sequences. Previous ArticleNext Article Volume 10Issue 71 July 1991In this issue RelatedDetailsLoading ...