Artigo Revisado por pares

Micro-Computed Tomography Assessment of Human Alveolar Bone: Bone Density and Three-Dimensional Micro-Architecture

2013; Wiley; Volume: 17; Issue: 2 Linguagem: Inglês

10.1111/cid.12109

ISSN

1708-8208

Autores

Yoon Jeong Kim, Jeffrey M. Henkin,

Tópico(s)

Bone health and osteoporosis research

Resumo

Clinical Implant Dentistry and Related ResearchVolume 17, Issue 2 p. 307-313 ARTICLE Micro-Computed Tomography Assessment of Human Alveolar Bone: Bone Density and Three-Dimensional Micro-Architecture Yoon Jeong Kim DDS, MS, Corresponding Author Yoon Jeong Kim DDS, MS Department of Periodontics, School of Dentistry, Loma Linda University, Loma Linda, CA, USAReprint requests: Dr. Yoon Jeong Kim, Periodontics, Loma Linda University, 24860 Taylor Street, Loma Linda, CA 92354, USA; e-mail: ykim02d2@llu.eduSearch for more papers by this authorJeffrey Henkin DDS, MS, Jeffrey Henkin DDS, MS Department of Periodontics, School of Dentistry, Loma Linda University, Loma Linda, CA, USASearch for more papers by this author Yoon Jeong Kim DDS, MS, Corresponding Author Yoon Jeong Kim DDS, MS Department of Periodontics, School of Dentistry, Loma Linda University, Loma Linda, CA, USAReprint requests: Dr. Yoon Jeong Kim, Periodontics, Loma Linda University, 24860 Taylor Street, Loma Linda, CA 92354, USA; e-mail: ykim02d2@llu.eduSearch for more papers by this authorJeffrey Henkin DDS, MS, Jeffrey Henkin DDS, MS Department of Periodontics, School of Dentistry, Loma Linda University, Loma Linda, CA, USASearch for more papers by this author First published: 09 July 2013 https://doi.org/10.1111/cid.12109Citations: 29 Part of this study was presented at the annual meeting of the American Academy of Periodontology in Hawaii, 2010. This study was funded by a Faculty Seed Grant at Loma Linda University. There is no conflict of interest related to this study. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Background: Micro-computed tomography (micro-CT) is a valuable means to evaluate and secure information related to bone density and quality in human necropsy samples and small live animals. Purpose: The aim of this study was to assess the bone density of the alveolar jaw bones in human cadaver, using micro-CT. The correlation between bone density and three-dimensional micro architecture of trabecular bone was evaluated. Materials and Methods: Thirty-four human cadaver jaw bone specimens were harvested. Each specimen was scanned with micro-CT at resolution of 10.5 μm. The bone volume fraction (BV/TV) and the bone mineral density (BMD) value within a volume of interest were measured. The three-dimensional micro architecture of trabecular bone was assessed. All the parameters in the maxilla and the mandible were subject to comparison. The variables for the bone density and the three-dimensional micro architecture were analyzed for nonparametric correlation using Spearman's rho at the significance level of p < .05. Results: A wide range of bone density was observed. There was a significant difference between the maxilla and mandible. All micro architecture parameters were consistently higher in the mandible, up to 3.3 times greater than those in the maxilla. The most linear correlation was observed between BV/TV and BMD, with Spearman's rho = 0.99 (p = .01). Both BV/TV and BMD were highly correlated with all micro architecture parameters with Spearman's rho above 0.74 (p = .01). Conclusions: Two aspects of bone density using micro-CT, the BV/TV and BMD, are highly correlated with three-dimensional micro architecture parameters, which represent the quality of trabecular bone. This noninvasive method may adequately enhance evaluation of the alveolar bone. Citing Literature Volume17, Issue2April 2015Pages 307-313 RelatedInformation

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