Artigo Acesso aberto Revisado por pares

Nucleotide sequence and functions of mrk determinants necessary for expression of type 3 fimbriae in Klebsiella pneumoniae

1991; American Society for Microbiology; Volume: 173; Issue: 2 Linguagem: Inglês

10.1128/jb.173.2.916-920.1991

ISSN

1098-5530

Autores

Bradley L. Allen, G F Gerlach, Steven Clegg,

Tópico(s)

Bacterial Genetics and Biotechnology

Resumo

The nucleotide sequence of six genes involved in the expression of type 3 fimbriae of Klebsiella pneumoniae was determined. In addition to the genes that encode the fimbrial subunit (mrkA) and adhesion (mrkD), the mrkB, mrkC, and mrkE genes appear to be involved in assembly of the fimbrial filament and regulation of type 3 fimbrial expression. The mrkF gene product is required to maintain the stability of the fimbrial filament on the cell surface.

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