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Is it time to reconsider initial antibiotic treatment strategies for severe urinary tract infections in Europe?

2007; Elsevier BV; Volume: 13; Issue: 3 Linguagem: Inglês

10.1111/j.1469-0691.2007.01666.x

1469-0691

Jean‐Ralph Zahar, Marc Lecuit, Étienne Carbonnelle, Florence Ribadeau-Dumas, Xavier Nassif, Olivier Lortholary,

Antibiotic Resistance in Bacteria

Until recently, most reported cases of bacteraemia caused by multidrug-resistant strains of Enterobacteriacae producing an extended-spectrum beta-lactamase (ESBL) in Europe have been nosocomial in origin. However, increasing numbers of reports of community-acquired bacteraemia and urinary tract infection caused by ESBL-producing microorganisms suggest that the geographical origin of patients should be taken into account as a risk-factor for possible ESBL production. Early identification of patients at high-risk of infection with ESBL-producing microorganisms, based on their geographical origin and travel history, should help to optimise initial antibiotic treatment strategies for severe urinary tract infections in Europe.