Inhibición in vitro de las enzimas alfa-amilasa y lipasa pancreática por fracciones fenólicas de extractos etanólicos de hojas de Yacón (Smallanthus sonchifolius Poepp. & Endl).
2015; Universidad de Los Andes; Volume: 10; Issue: 1 Linguagem: Inglês
ISSN
1856-5301
AutoresDary Luz Mendoza Meza, Ramón Medina Valdés,
Tópico(s)Microbial Metabolites in Food Biotechnology
ResumoYacon is an Andean crop with antioxidant and dietary properties. In this study the ethanolic extracts were obtained from yacon leaves collected in Chia (Cundinamarca) and San Francisco (Antioquia), Colombia. The maximum content of total phenols and flavonoids was 11.6 ± 0.4 mg GAE/mL and 0.37 ? 0.03 mg QE/mL to Chia; 5.04 ± 0.13 mg GAE/mL and 0.21 ? 0.03 mg QE/mL to San Francisco. All samples showed in vitro inhibition of pancreatic alpha-amylase and lipase enzymes. HPLC-MS analysis showed pseudomolecular ions corresponding to quercetin and chlorogenic acid, ferulic, caffeic and quinic. The results suggest that yacon leaves contain metabolites that could be used as an alternative for controlling obesity.
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