Artigo Acesso aberto Revisado por pares

Bitis gabonica Venom

1974; Elsevier BV; Volume: 249; Issue: 12 Linguagem: Inglês

10.1016/s0021-9258(19)42549-0

ISSN

1083-351X

Autores

Dawie P. Botes, Cornelis C. Viljoen,

Tópico(s)

Venomous Animal Envenomation and Studies

Resumo

Abstract Bitis gabonica phospholipase A contains 118 amino acid residues in a single chain and is cross-linked by six disulfide bridges. Cyanogen bromide cleavage, and tryptic and chymotryptic digests provided the necessary overlapping peptides allowing the derivation of the complete amino acid sequence. In its primary structure the enzyme is more closely related to porcine pancreatic phospholipase A than to the enzyme from the honey bee Apis mellifica.

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