Plasma Troponin T and Troponin I after Minimally Invasive Coronary Bypass Surgery
2000; American Association for Clinical Chemistry; Volume: 46; Issue: 2 Linguagem: Inglês
10.1093/clinchem/46.2.279
ISSN1530-8561
AutoresSiegmund Braun, A Barankay, Domenico Mazzitelli,
Tópico(s)Cardiac Ischemia and Reperfusion
ResumoIn the last decade, plasma cardiac troponin T (cTnT) and cardiac troponin I (cTnI) have been identified as specific and sensitive markers of myocardial cell injury (1)(2). During most types of cardiac surgery, some degree of myocardial injury regularly occurs that is dependent on multiple factors, such as the type and extent of the surgical procedure, the method of myocardial protection, the preoperative cardiac status of the patient, and the anesthetic procedures (3)(4). In recent years, minimally invasive direct coronary artery bypass grafting (MIDCAB) and off-pump coronary artery bypass grafting (OPCAB) have been introduced as alternative methods to coronary artery bypass grafting (CABG) (5). The potential advantages of MIDCAB and OPCAB arise from the avoidance of cardiopulmonary bypass (CPB) and cardioplegia. CPB always induces a systemic inflammatory response syndrome, and a substantial number of patients develop multiple organ dysfunction. However, there are also disadvantages of MIDCAB and OPCAB, including difficulty of performing the coronary anastomosis on the beating heart, ischemic damage during occlusion of the targeted vessel, and cardiac dislocation or compression to obtain optimal exposure of the vessels on the posterior wall. Currently, only limited data (6)(7)(8)(9) concerning the release of troponins during MIDCAB …
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