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Cutaneous Lymphoma International Consortium Study of Outcome in Advanced Stages of Mycosis Fungoides and Sézary Syndrome: Effect of Specific Prognostic Markers on Survival and Development of a Prognostic Model

2015; Lippincott Williams & Wilkins; Volume: 33; Issue: 32 Linguagem: Inglês

10.1200/jco.2015.61.7142

1527-7755

Julia Scarisbrick, H. Miles Prince, Maarten H. Vermeer, Pietro Quaglino, Sarah McCue Horwitz, Pierluigi Porcu, Rudolf Stadler, Gary S. Wood, M. Beylot‐Barry, Anne Pham‐Ledard, Francine M. Foss, Michael Girardi, M. Bagot, Laurence Michel, Maxime Battistella, Joan Guitart, Timothy M. Kuzel, Maria Estela Martínez‐Escala, Teresa Estrach, Evangelia Papadavid, Christina Antoniou, Dimitis Rigopoulos, Vassilki Nikolaou, Makoto Sugaya, Tomomitsu Miyagaki, Robert Gniadecki, José Antônio Sanches, Jade Cury‐Martins, Denis Miyashiro, Octavio Servitje, Cristina Muniesa, Emilio Berti, Francesco Onida, Laura Corti, Emilia Hodak, Iris Amitay‐Laish, Pablo L. Ortiz‐Romero, José Luis Rodríguez‐­Peralto, Robert Knobler, Stefanie Porkert, Wolfgang Bauer, Nicola Pimpinelli, Vieri Grandi, Richard Cowan, Alain H. Rook, Ellen Kim, Alessandro Pileri, Annalisa Patrizi, Ramón M. Pujol, Henry K. Wong, Kelly Tyler, R. Stranzenbach, Christiane Querfeld, Paolo Fava, Milena Maule, Rein Willemze, Felicity Evison, Stephen Morris, Robert Twigger, Rakhshandra Talpur, Jinah Kim, G. Ognibene, Shufeng Li, Mahkam Tavallaee, Richard T. Hoppe, Madeleine Duvic, Sean Whittaker, Youn H. Kim,

Lymphoma Diagnosis and Treatment

Advanced-stage mycosis fungoides (MF; stage IIB to IV) and Sézary syndrome (SS) are aggressive lymphomas with a median survival of 1 to 5 years. Clinical management is stage based; however, there is wide range of outcome within stages. Published prognostic studies in MF/SS have been single-center trials. Because of the rarity of MF/SS, only a large collaboration would power a study to identify independent prognostic markers.