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Protein–DNA interaction: impedance study of MutS binding to a DNA mismatch

2004; Royal Society of Chemistry; Issue: 5 Linguagem: Inglês

10.1039/b314642a

1364-548X

Chen-Zhong Li, Yi‐Tao Long, Jeremy S. Lee, Heinz‐Bernhard Kraatz,

DNA and Nucleic Acid Chemistry

MutS binding to a double-stranded DNA containing a single nucleotide mismatch can be conveniently monitored by impedance spectroscopy and represents the first step in developing an electrochemical binding essay for single nucleotide mismatch detection.