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Profile of acute kidney injury after open heart surgeries in a tertiary care hospital

2015; Medknow; Volume: 26; Issue: 6 Linguagem: Inglês

10.4103/1319-2442.168601

2320-3838

HilalA Malla, FayazA Rather, SaleemM Najar, AG Ahangar, HilalM Bhat, ImtiyazA Wani,

Cardiac and Coronary Surgery Techniques

Our objective is to determine the incidence, etiology, risk factors and outcome of acute kidney injury (AKI) after open heart surgery. A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence, etiology and outcome. Post-operative AKI was considered when the post-operative serum creatinine was >1.5 mg/dL or there was doubling of serum creatinine above the baseline (pre-operative) with a prior normal renal function. The incidence of AKI in the post-operative period in our study was 17.7%. The common etiological factors for AKI in our study were sepsis, hypotension, prolonged need for ventilator and inotropic support and drugs given in the post-operative period. The important risk factors for the development of AKI in the post-operative period were hypertension, diabetes mellitus, gout, prolonged total bypass time and prolonged aortic cross-clamp time. The overall mortality in our study subjects was 11.3% (seven of 62 died) and the mortality in the patients who developed post-operative AKI was 71.4%.