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Cannula-related infection in adult medical intensive care unit patients undergoing extracorporeal life support and extracorporeal membrane oxygenation

2015; Elsevier BV; Volume: 91; Issue: 4 Linguagem: Inglês

10.1016/j.jhin.2015.08.022

1532-2939

Kathrin Hahne, C. Horstmann, Dieter Fischer, Robin Köck, G. Peters, Pia Lebiedz,

Nosocomial Infections in ICU

Catheter-related bloodstream infections (BSIs) in intensive care units (ICUs) increase mortality, duration of ICU stay and healthcare costs. 1 Lambert M.L. Suetens C. Savey A. et al. Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study. Lancet Infect Dis. 2011; 11: 30-38 Abstract Full Text Full Text PDF PubMed Scopus (288) Google Scholar Multiple studies have evaluated measures to reduce these infections. 2 Palomar M. Alvarez-Lerma F. Riera A. et al. Impact of a national multimodal intervention to prevent catheter-related bloodstream infection in the ICU: the Spanish experience. Crit Care Med. 2013; 41: 2364-2372 Crossref PubMed Scopus (109) Google Scholar Extracorporeal circulation (EC) for lung (ECMO: extracorporeal membrane oxygenation; PECLA: pumpless extracorporeal lung assistance) or cardiac assistance (ECLS: extracorporeal life support) is of growing importance and is increasingly used in intensive care medicine. 3 Dalton H.J. Extracorporeal life support: moving at the speed of light. Respir Care. 2011; 56: 1445-1453 Crossref PubMed Scopus (49) Google Scholar However, data on ECMO- and ECLS-associated BSI are rare. Schmidt et al. found a cannula-associated BSI rate of 10% in cardiogenic shock adults with need for ECLS support. 4 Schmidt M. Bréchot N. Hariri S. et al. Nosocomial infections in adult cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation. Clin Infect Dis. 2012; 55: 1633-1641 Crossref PubMed Scopus (201) Google Scholar