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BIBTEX RIS

Plasmid-cured Salmonella enteritidis AL1192 as a candidate for a live vaccine

1985; American Society for Microbiology; Volume: 50; Issue: 2 Linguagem: Inglês

10.1128/iai.50.2.586-587.1985

ISSN

1098-5522

Autores

Morihiko Nakamura, Shizuo Sato, Tatsuo Ohya, Shuichi Suzuki, Sumio Ikeda, Tetsuo Koeda,

Tópico(s)

Vibrio bacteria research studies

Resumo

We report the immunizing capacity of Salmonella enteritidis AL1192, a strain that has been cured of a 36-megadalton plasmid, to protect ddY mice against subsequent challenge with virulent salmonellas. This strain, which was given subcutaneously at a dose of 10(6) organisms, provided significant protection against oral, subcutaneous, or intraperitoneal challenge by virulent wild-type strains of not only S. enteritidis, but also S. dublin, S. naestved, and S. typhimurium.

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