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Use of capsule endoscopy in patients with C rohn's disease in J apan: A multicenter survey

2013; Wiley; Volume: 29; Issue: 1 Linguagem: Inglês

10.1111/jgh.12411

1440-1746

Motohiro Esaki, Takayuki Matsumoto, Kenji Watanabe, Tetsuo Arakawa, Yuji Naito, Minoru Matsuura, Hiroshi Nakase, Toshifumi Hibi∥, Takayuki Matsumoto, Sadaharu Nouda, Kazuhide Higuchi, Naoki Ohmiya, Hidemi Goto, Sei Kurokawa, Satoshi Motoya, Mamoru Watanabe,

Gastrointestinal disorders and treatments

Abstract Background and Aim Until the approval of patency capsule, capsule endoscopy ( CE ) has not been routinely applied for the diagnosis of C rohn's disease ( CD ) in J apan. We aimed to survey current situation of CE use for patients with CD in J apan. Methods The nationwide survey of 40 J apanese institutions identified 94 patients with established CD (e CD ) and 80 patients with suspected CD (s CD ), who were examined by CE . Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In s CD , final diagnosis after CE was also analyzed. Results Patients with e CD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with e CD of colitis type had ileal lesions under CE , thereby being reclassified as ileocolitis type. In patients with s CD , CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with s CD , who were diagnosed as not having CD . Capsule retention rate was not statistically different between patients with e CD and those with s CD (7.4% vs 6.3%, P = 1.0). Conclusions CE is useful for the evaluation of small bowel mucosal injuries in J apanese patients with s CD and e CD . Possible intestinal stricture needs to be carefully evaluated before CE even in patients with s CD .