Produção Nacional
Revisado por pares
Bioactivity of the compounds isolated from Blepharocalyx salicifolius
2011; Springer Science+Business Media; Volume: 21; Issue: 4 Linguagem: Inglês
10.1590/s0102-695x2011005000111
ISSN1981-528X
AutoresEzequias Pessoa de Siqueira, Djalma Menezes de Oliveira, Susana Johann, Patrícia Silva Cisalpino, Betânia Barros Cota, Ana Rabello, Tânia Maria de Almeida Alves, Carlos Leomar Zani,
Tópico(s)Phytochemical compounds biological activities
ResumoBlepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 µg.mL-1 and Paracoccidioides brasiliensis from 3.10 to 12.5 µg.mL-1.
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