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Melatonin as an antioxidant: physiology versus pharmacology

2005; Wiley; Volume: 39; Issue: 2 Linguagem: Inglês

10.1111/j.1600-079x.2005.00261.x

1600-079X

Rüssel J. Reiter, Dun‐Xian Tan, María Dolores Maldonado y Aibar,

Plant Parasitism and Resistance

Journal of Pineal ResearchVolume 39, Issue 2 p. 215-216 Melatonin as an antioxidant: physiology versus pharmacology Russel J. Reiter, Russel J. Reiter Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio, TX 78229-3900, USA E-mail: [email protected]Search for more papers by this authorDun-Xian Tan, Dun-Xian Tan Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio, TX 78229-3900, USA E-mail: [email protected]Search for more papers by this authorMaria D. Maldonado, Maria D. Maldonado Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio, TX 78229-3900, USA E-mail: [email protected]Search for more papers by this author Russel J. Reiter, Russel J. Reiter Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio, TX 78229-3900, USA E-mail: [email protected]Search for more papers by this authorDun-Xian Tan, Dun-Xian Tan Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio, TX 78229-3900, USA E-mail: [email protected]Search for more papers by this authorMaria D. Maldonado, Maria D. Maldonado Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio, TX 78229-3900, USA E-mail: [email protected]Search for more papers by this author First published: 06 July 2005 https://doi.org/10.1111/j.1600-079X.2005.00261.xCitations: 159Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1 Wurtman RJ. Melatonin. In: Encyclopedia of Dietary Supplements. JA Schwart, Ed, Marcel Dekker, New York, 2005; pp. 457–466. 2 Terron MP, Marchena JM, Shadi F, Harvey S, Lea RW, Rodriguez AB. Melatonin: an antioxidant at physiological concentrations. J Pineal Res 2001; 31: 95–96. 3 Antolin I, Obst B, Burkhardt S, Hardeland R. Antioxidative properties in a high-melatonin organism: the dinoflagellate Gonyaulax polyedra is rescued from lethal oxidative stress by strongly elevated, but physiologically possible concentrations of melatonin. J Pineal Res 1997; 23: 182–190. 4 Manev H, Uz T, Kharlamov A, Joo JY. Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats. FASEB J 1996; 10: 1546–1551. 5 Skaper SD, Floreani M, Ceccon M, Facci L, Giusti P. Excitotoxicity, oxidative stress, and neuroprotective potential of melatonin. Ann N Y Acad Sci 1999; 890: 107–118. 6 Parlakpinar H, Ozer MK, Sahna E, Vardi N, Cigremis Y, Acet A. Amikacin-induced acute renal injury in rats: protective role of melatonin. J Pineal Res 2003; 35: 85–90. 7 Reiter RJ, Tan DX. What constitutes a physiological concentration of melatonin? J Pineal Res 2003; 34: 79–80. 8 Tan DX, Manchester LC, Reiter RJ et al. High physiological concentrations of melatonin in bile of mammals. Life Sci 1999; 65: 2523–2529. 9 Skinner DC, Malpaux B. High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology 1999; 140: 4399–4405. 10 Montilla P, Cruz A, Padillo FJ et al. Melatonin versus vitamin E as a protective treatment against oxidative stress after extra-hepatic bile duct ligation in rats. J Pineal Res 2001; 31: 138–144. 11 Martinez-Cruz F, Pozo D, Osuna C, Espinar A, Marchante C, Guerrero JM. Oxidative stress induced by phenylketonuria in the rat: prevention by melatonin, vitamin E and vitamin C. J Neurosci Res 2002; 69: 550–558. 12 Baydas G, Canatan H, Turkoglu A. Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus. J Pineal Res 2002; 32: 225–230. 13 Gitto E, Karbownik M, Reiter RJ et al. Effects of melatonin treatment in septic newborns. Pediatr Res 2001; 50: 56–60. 14 Gitto E, Reiter RJ, Cordaro SP et al. Oxidative and inflammatory parameters in respiratory distress syndrome of preterm infants. Am J Perinatol 2004; 21: 209–216. Citing Literature Volume39, Issue2September 2005Pages 215-216 ReferencesRelatedInformation