Portal de Periódicos da CAPES

Hepatitis E virus genotype 3f in pigs in New Caledonia

2011; Wiley; Volume: 89; Issue: 12 Linguagem: Inglês

10.1111/j.1751-0813.2011.00848.x

1751-0813

Mamadou Kaba, Bernard Davoust, Olivier Cabre, Philippe Colson,

Liver Disease and Transplantation

Background Hepatitis E virus (HEV) is highly prevalent in farm pigs worldwide and an increasing body of data from industrialised countries suggests that it is an agent of a porcine zoonosis. Methods We used in‐house real‐time reverse transcription polymerase chain reaction to study HEV infection in 4–26‐week‐old pigs on a pig farm in New Caledonia, Oceania, for which no data are available. Results HEV RNA was detected in faeces from 6 of 92 (6.5%) pigs tested and all were 9–16 weeks old. Phylogenetic analysis showed that the HEV open reading frame 1 and 2 sequences recovered in this study formed a single cluster among HEV genotype 3 subtype f. Conclusions Our work shows for the first time that pigs are a reservoir for HEV in New Caledonia. Further studies are needed to assess the prevalence and phylogenetic relationships of HEV in pigs and humans in this French overseas collectivity.