Produção Nacional
Revisado por pares
Natural products with antileprotic activity
2007; Springer Science+Business Media; Volume: 17; Issue: 1 Linguagem: Inglês
10.1590/s0102-695x2007000100022
ISSN1981-528X
AutoresJosé Maria Barbosa‐Filho, Francisco A. do Nascimento Júnior, Anna Cláudia de Andrade Tomaz, Petrônio Filgueiras de Athayde-Filho, Marcelo Sobral da Silva, Emídio Vasconcelos Leitão da Cunha, María de Fátima Vanderlei de Souza, Leônia Maria Batista, Margareth de Fátima Formiga Melo Diniz,
Tópico(s)Phytochemistry Medicinal Plant Applications
ResumoLeprosy is a chronic infectious disease caused by Mycobacterium leprae bacillus. It was considered to be an incurable disease for ages. Nowadays leprosy is a vanishing disease although we can meet it principally in the tropical zone countries. Brazil has the second greatest number of leprosy cases around the world with almost 30,000 new cases diagnosed in 2005. The present work constitutes a literature review on plant extracts and chemically defined molecules of natural origin showing antileprotic activity. The review refers to 11 plants, their families, and geographical distribution, the utilized parts, the type of extract and the tested organism. It also includes 17 compounds isolated from higher plants and microorganisms, classified into appropriate chemical groups. Some aspects of recent antileprotic-activity-directed research on natural products are discussed. For this purpose 63 references were consulted.
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