Portal de Periódicos da CAPES

Artigo Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil: data from the Brazilian Type 1 Diabetes Study Group

2015; BioMed Central; Volume: 7; Issue: 1 Linguagem: Inglês

10.1186/s13098-015-0081-9

1758-5996

João Soares Felício, Ana Carolina Contente Braga de Souza, Camila Cavalcante Koury, João Felício Abrahão Neto, Karem Barbosa Miléo, Flávia Marques Santos, Ana Regina Bastos Motta, Denisson Dias Silva, Thaís Pontes Arbage, Carolina Tavares Carvalho, Hana Andrade de Rider Brito, Elizabeth Sumi Yamada, Roberta Arnoldi Cobas, Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Catia C. Sousa Palma, Letícia Japiassú, João Régis Ivar Carneiro, Melanie Rodacki, Lenita Zajdenverg, Neuza B. C. de Araújo, Marilena de Menezes Cordeiro, Jorge Luiz Luescher, Renata Szundy Berardo, Márcia Nery, Catarina Gomes Cani, Maria do Carmo Arruda Marques, Luís Eduardo Calliari, Renata Maria de Noronha, Thaís Della Manna, Roberta Diaz Savoldelli, Fernanda G Penha, Milton César Foss, Maria Cristina Foss‐Freitas, António Pires, Fernando César Robles, Carlos Antônio Negrato, Maria de Fátima S Guedes, Sérgio Atala Dib, Patrícia Médici Dualib, Saulo Cavalcanti da Silva, Janice Sepúlveda, Emerson Sampaio, Rosângela Réa, Ana Cristina Ravazzani de Almeida Faria, Balduíno Tschiedel, Suzana Lavigne, Gustavo A Cardozo, Mirela Jobim de Azevedo, Luís Henrique Santos Canani, Alessandra Teixeira Netto Zucatti, Marisa Helena César Coral, Daniela Aline Pereira, Luiz Antônio de Araújo, Hermelinda Cordeiro Pedrosa, Monica Tolentino, Flaviene Alves do Prado, Nelson Rassi, Leticia B Araujo, Reine Marie Chaves Fonseca, Alexis Dourado Guedes, Odelisa Silva de Mattos, Manuel dos Santos Faria, Rossana Santiago de Sousa Azulay, Adriana Costa e Forti, Cristina Figueiredo Sampaio Façanha, Renan Magalhães Montenegro, Ana Paula Dias Rangel Montenegro, Naira Horta Melo, Karla Freire Rezende, Alberto Ramos, Déborah Laredo Jezini, Marília Brito Gomes,

Medication Adherence and Compliance

In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North-Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities.