Bacterial phagocytosis by macrophages from lipopolysaccharide responder and nonresponder mouse strains
1980; American Society for Microbiology; Volume: 28; Issue: 3 Linguagem: Inglês
10.1128/iai.28.3.762-765.1980
ISSN1098-5522
AutoresAnnamaria Cuffini, Nicola Carlone, G Forni,
Tópico(s)Immune Cell Function and Interaction
ResumoThe phagocytic capacity of macrophages from C3H/H3J mice was assessed against lipopolysaccharide-producing (Escherichia coli) and -nonproducing (Staphylococcus aureus) bacteria. Despite their gene-coded unresponsiveness to lipopolysaccharide endotoxin and lymphokines and their defective tumoricidal activity, proteose peptone-induced C3H/HeJ macrophages did not display a defective phagocytic capacity, but rather displayed an enhanced phagocytosis of both bacterial strains compared with macrophages from closely related C3H/HeN mice. Unstimulated peritoneal resident C3H/HeJ macrophages, on the other hand, displayed a normal phagocytic activity toward E. coli and enhanced phagocytosis toward S. aureus.
Referência(s)