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Suicide by Gabapentin Overdose

2011; Wiley; Volume: 56; Issue: 5 Linguagem: Inglês

10.1111/j.1556-4029.2011.01798.x

1556-4029

Owen Middleton,

Epilepsy research and treatment

Journal of Forensic SciencesVolume 56, Issue 5 p. 1373-1375 CASE REPORTPATHOLOGY/BIOLOGY; TOXICOLOGY Suicide by Gabapentin Overdose Owen Middleton M.D., Owen Middleton M.D. Hennepin County Medical Examiner’s Office, 530 Chicago Avenue, Minneapolis, MN 55415.Search for more papers by this author Owen Middleton M.D., Owen Middleton M.D. Hennepin County Medical Examiner’s Office, 530 Chicago Avenue, Minneapolis, MN 55415.Search for more papers by this author First published: 06 May 2011 https://doi.org/10.1111/j.1556-4029.2011.01798.xCitations: 39 Additional information and reprint requests:Owen Middleton, M.D.Hennepin County Medical Examiner’s Office530 Chicago AvenueMinneapolis, MN 55415E-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Abstract: Gabapentin is an antiepileptic drug that is prescribed for both FDA-approved and multiple off-label conditions, and has a relatively safe side-effect profile. Rare cases of overdose-related adverse effects have been reported in the literature. Described herein are the circumstances and autopsy findings of a 62-year-old woman with a history of depression, whose death was caused by intentional ingestion of excess gabapentin. The postmortem peripheral blood gabapentin concentration as determined by high-performance liquid chromatography/tandem mass spectroscopy was 88 μg/mL. Previously reported cases of individuals surviving gabapentin overdoses are discussed and compared with this case. Based on a review of the available literature, this appears to be the first published report of a death due solely to gabapentin toxicity. References 1 Baselt RC. Gabapentin. 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