6‐Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase‐9 expression via blockade of nuclear factor‐κB activation

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6‐Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase‐9 expression via blockade of nuclear factor‐κB activation

2010; Wiley; Volume: 161; Issue: 8 Linguagem: Inglês

10.1111/j.1476-5381.2010.00991.x

ISSN

1476-5381

Autores

Hui Ling, Hongyuan Yang, S‐H Tan, W.‐K. Chui, Eh Piew Chew,

Tópico(s)

Natural Compounds in Disease Treatment

Resumo

Shogaols are reported to possess anti-inflammatory and anticancer activities. However, the antimetastatic potential of shogaols remains unexplored. This study was performed to assess the effects of shogaols against breast cancer cell invasion and to investigate the underlying mechanisms.

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6‐Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase‐9 expression via blockade of nuclear factor‐κB activation