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Deproteinized bovine bone in association with guided tissue regeneration or enamel matrix derivatives procedures in aggressive periodontitis patients: a 1‐year retrospective study

2015; Wiley; Volume: 42; Issue: 6 Linguagem: Inglês

10.1111/jcpe.12413

1600-051X

Zvi Artzi, Haim Tal, Ori Platner, Nadav Wasersprung, Evgeny Weinberg, Gil Slutzkey, Nir Gozali, Guy Carmeli, Ran Herzberg, Avital Kozlovsky,

HIV/AIDS oral health manifestations

Abstract Objectives To retrospectively evaluate and compare two regenerative periodontal procedures in young individuals with aggressive periodontitis (AgP). Methods Thirty‐two patients aged 14–25 years (mean ± SD 19.3 ± 5.7) were diagnosed as having AgP with multiple intra‐bony defects ( IBD s) and treated by one of two regenerative modalities of periodontal therapy: guided tissue regeneration ( GTR ) using deproteinized bone xenograft ( DBX ) particles and a resorbable membrane (the GTR group), or an application of enamel matrix derivatives ( EMD ) combined with DBX (the EMD / DBX group). Periodic monitoring of treated sites included recording of probing depth ( PD ), clinical attachment level ( CAL ) and gingival recession. Pre‐treatment and 1‐year post‐operative findings were statistically analysed within and between groups. Results The PD and CAL values decreased significantly with time, but not those between study groups. The mean pre‐treatment and 1‐year post‐treatment PD s of the IBD s of the GTR group ( n = 16; sites = 67) were 8.93 ± 1.14 mm and 3.58 ± 0.50 mm, respectively, and the mean CAL s were 9.03 ± 1.03 mm and 4.16 ± 0.53 mm respectively. The mean PD s of the EMD / DBX group ( n = 16; sites = 73) were 8.77 ± 1.04 mm and 3.61 ± 0.36 mm, respectively, and the mean CALS were 8.79 ± 1.04 mm and 3.77 ± 0.22 mm respectively ( p < 0.001 for all). Conclusion Surgical treatment of AgP patients by either GTR or by application of EMD / DBX yielded similarly successful clinical results at 1‐year post‐treatment.