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Epidemiology and Diagnosis of Health Care–Associated Infections in the NICU

2012; American Academy of Pediatrics; Volume: 129; Issue: 4 Linguagem: Inglês

10.1542/peds.2012-0147

1098-4275

Richard A. Polin, Susan E. Denson, Michael T. Brady, Lu Ann Papile, Jill E. Baley, Waldemar A. Carlo, James J. Cummings, Praveen Kumar, Rosemarie C. Tan, Kristi L. Watterberg, Wanda D. Barfield, Ann L. Jefferies, George A. Macones, Rosalie O. Mainous, Tonse N.K. Raju, Kasper S. Wang, Jim Couto, Carrie L. Byington, H. Dele Davies, Kathryn M. Edwards, Mary P. Glodé, Mary Anne Jackson, Harry L. Keyserling, Yvonne A. Maldonado, Dennis L. Murray, Walter A. Orenstein, Gordon E. Schutze, Rodney E. Willoughby, Theoklis E. Zaoutis, Marc A. Fischer, Bruce G. Gellin, Richard L. Gorman, Lucia Lee, R. Douglas Pratt, Jennifer S. Read, J. Ben Robinson, Marco Aurélio Palazzi Sáfadi, Jane F. Seward, Jeffrey R. Starke, Geoffrey R. Simon, Tina Q. Tan, Carol J. Baker, Henry H. Bernstein, David W. Kimberlin, Sarah S. Long, H. Cody Meissner, Larry K. Pickering, Lorry G. Rubin, Jennifer M. Frantz,

Antibiotic Use and Resistance

This Technical Report was reaffirmed March 2023. Health care−associated infections in the NICU are a major clinical problem resulting in increased morbidity and mortality, prolonged length of hospital stays, and increased medical costs. Neonates are at high risk for health care−associated infections because of impaired host defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of neonatal skin, the use of invasive procedures and devices, and frequent exposure to broad-spectrum antibiotics. This statement will review the epidemiology and diagnosis of health care−associated infections in newborn infants.