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BIBTEX RIS

Role of Keratinocyte Injury in Adherence of Streptococcus pyogenes

1999; American Society for Microbiology; Volume: 67; Issue: 12 Linguagem: Inglês

10.1128/iai.67.12.6707-6709.1999

ISSN

1098-5522

Autores

Gary L. Darmstadt, Laurel Mentele, Philip Fleckman, Craig E. Rubens,

Tópico(s)

Dermatology and Skin Diseases

Resumo

ABSTRACT Keratinocytes injured acutely by UVB light or lipopolysaccharide were used to test the hypothesis that keratinocyte injury promotes bacterial adherence and the development of group A streptococcal skin infections. Injury did not affect adherence to undifferentiated and differentiated keratinocytes, but keratinocyte differentiation promoted adherence four- to fivefold.

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