Artigo Acesso aberto Revisado por pares

Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation

2015; American Association for the Advancement of Science; Volume: 8; Issue: 385 Linguagem: Inglês

10.1126/scisignal.aaa5208

ISSN

1937-9145

Autores

Cheng Zhang, Brooks Taylor, Diana R. Ourthiague, Alexander Hoffmann,

Tópico(s)

Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Resumo

Mathematical modeling and imaging analysis reveal the relative contributions of two adaptor proteins to the activation of NF-κB in macrophages.

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