Artigo Revisado por pares

The Synthesis of Racemic Ambrox ®

1989; Wiley; Volume: 72; Issue: 5 Linguagem: Inglês

10.1002/hlca.19890720517

ISSN

1522-2675

Autores

G. Büchi, Hans Wüest,

Tópico(s)

Phytochemistry and Biological Activities

Resumo

Abstract (±)‐ Ambrox ( 10 ), the racemic form of (−)‐ Ambrox ®, the commercially most important ambergris odorant has been synthesized from a readily available bicyclic keto ester in five steps. The racemic ether retains the characteristic scent of fine‐quality ambergis, and the odor threshold of the racemate and the (−)‐enantiomer prepared from natural sclareol were found to be essentially identical.

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