Portal de Periódicos da CAPES

Legg-Calvé-Perthes Disease

2010; Volume: 18; Issue: 11 Linguagem: Inglês

10.5435/00124635-201011000-00005

1940-5480

Harry K.W. Kim,

Bone and Joint Diseases

Legg-Calvé-Perthes disease is an idiopathic hip disorder that produces ischemic necrosis of the growing femoral head. Permanent femoral head deformity is the most significant sequela. Experimental studies indicate that the pathologic repair process, which is marked by an imbalance of bone resorption and formation, contributes to the pathogenesis of femoral head deformity. Important prognostic factors include degree of deformity, age at disease onset, extent of head involvement, head-at-risk signs, and lateral pillar collapse. Treatment should be guided by age at disease onset, current best evidence, and prognostic factors. Patients aged 8 years), indicating the need to develop more effective treatments based on the pathobiology of the disease.