Knee Ankyloses Associated with Tuberculosis from the Medieval Hungary - Differential Diagnosis Based on Medical Imaging Techniques
2012; Wiley; Volume: 25; Issue: 3 Linguagem: Inglês
10.1002/oa.2284
ISSN1099-1212
AutoresLászló Paja, Hélène Coqueugniot, Olivier Dutour, Renee Willmon, G. L. Farkas, András Palkó, György Pálfi,
Tópico(s)Hematological disorders and diagnostics
ResumoInternational Journal of OsteoarchaeologyVolume 25, Issue 3 p. 352-360 Short Report Knee Ankyloses Associated with Tuberculosis from the Medieval Hungary – Differential Diagnosis Based on Medical Imaging Techniques L. Paja, Corresponding Author L. Paja Department of Biological Anthropology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary National Heritage Protection Centre, Hungarian National Museum, Szeged, Hungary Laboratoire de Paléoanthropologie de l'EPHE, École Pratique des Hautes Études, Talence, France Correspondence to: László Paja, Department of Biological Anthropology, University of Szeged, H-6722, Egyetem utca 2, Szeged, Hungary. e-mail: [email protected]Search for more papers by this authorH. Coqueugniot, H. Coqueugniot UMR 5199 – PACEA, Talence, France Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, GermanySearch for more papers by this authorO. Dutour, O. Dutour Laboratoire de Paléoanthropologie de l'EPHE, École Pratique des Hautes Études, Talence, France Department of Anthropology, University of Toronto, Toronto, CanadaSearch for more papers by this authorR. Willmon, R. Willmon Laboratoire de Paléoanthropologie de l'EPHE, École Pratique des Hautes Études, Talence, France Department of Anthropology, University of Western Ontario, London, CanadaSearch for more papers by this authorG. L. Farkas, G. L. Farkas Department of Biological Anthropology, Faculty of Science and Informatics, University of Szeged, Szeged, HungarySearch for more papers by this authorA. Palkó, A. Palkó Department of Radiology, University of Szeged, Szeged, HungarySearch for more papers by this authorG. Pálfi, G. Pálfi Department of Biological Anthropology, Faculty of Science and Informatics, University of Szeged, Szeged, HungarySearch for more papers by this author L. Paja, Corresponding Author L. Paja Department of Biological Anthropology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary National Heritage Protection Centre, Hungarian National Museum, Szeged, Hungary Laboratoire de Paléoanthropologie de l'EPHE, École Pratique des Hautes Études, Talence, France Correspondence to: László Paja, Department of Biological Anthropology, University of Szeged, H-6722, Egyetem utca 2, Szeged, Hungary. e-mail: [email protected]Search for more papers by this authorH. Coqueugniot, H. Coqueugniot UMR 5199 – PACEA, Talence, France Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, GermanySearch for more papers by this authorO. Dutour, O. Dutour Laboratoire de Paléoanthropologie de l'EPHE, École Pratique des Hautes Études, Talence, France Department of Anthropology, University of Toronto, Toronto, CanadaSearch for more papers by this authorR. Willmon, R. Willmon Laboratoire de Paléoanthropologie de l'EPHE, École Pratique des Hautes Études, Talence, France Department of Anthropology, University of Western Ontario, London, CanadaSearch for more papers by this authorG. L. Farkas, G. L. Farkas Department of Biological Anthropology, Faculty of Science and Informatics, University of Szeged, Szeged, HungarySearch for more papers by this authorA. Palkó, A. Palkó Department of Radiology, University of Szeged, Szeged, HungarySearch for more papers by this authorG. Pálfi, G. Pálfi Department of Biological Anthropology, Faculty of Science and Informatics, University of Szeged, Szeged, HungarySearch for more papers by this author First published: 12 October 2012 https://doi.org/10.1002/oa.2284Citations: 4Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Osseous ankylosis of large joints that occurs secondary to infection is rarely described in developed countries, thanks to diagnostic techniques that allow early detection and treatment of the underlying infection. Evidence of the natural history and progression of the disease is now primarily studied through the observation and analysis of osteoarcheological specimens, and medical reports or books dating from the pre-antibiotic era. This report illustrates several cases where modern medical imaging techniques and ancient medical literature were successfully interpreted to diagnose rare, advanced-stage tuberculous alterations in osteoarcheological specimens. Two skeletons from the Bátmonostor cemetery (Hungary) demonstrate complete unilateral ankylosis of the knee. Macroscopic and radiographic examinations were undertaken to assess the extent of skeletal changes and determine their cause. Data obtained from computed tomography (CT) were constructed in 2D and 3D. The 2D CT images revealed cavities involving both the metaphyses and the epiphyses. The 3D reconstructions allowed us to reconstruct the more precise volumetric morphology of the circumscribed lytic lesions, as well as clear 'image-mirror' lacunar volumes. On the basis of the macroscopic and radiological analyses, extra-spinal tuberculous infection seems to have been the most probable etiology of these two cases. Copyright © 2012 John Wiley & Sons, Ltd. Citing Literature Volume25, Issue3May/June 2015Pages 352-360 RelatedInformation
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