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Artigo Revisado por pares
BIBTEX RIS

Diastereoselective Synthesis of β‐Nitro‐ and β‐Aminoalcohols

1981; Wiley; Volume: 20; Issue: 4 Linguagem: Inglês

10.1002/anie.198103971

ISSN

1521-3773

Autores

Dieter Seebàch, Albert K. Beck, Friedrich Lehr, Thomas Weller, Ernest W. Colvin,

Tópico(s)

Chemical Synthesis and Analysis

Resumo

Almost pure diastereoisomers of β-amino alcohols, important as synthons, can be prepared via the O-silylated nitroalcohols (1). Compounds (1) are accessible by protonation of the corresponding lithium salts or by addition of silylated aci-nitro derivatives R2CH = NO2Si tBuMe2 to aldehydes R1CHO.

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