Artigo Acesso aberto Revisado por pares

Flp recombinase regulated lacZ expression at the ROSA26 locus

2002; Wiley; Volume: 32; Issue: 2 Linguagem: Catalão

10.1002/gene.10039

ISSN

1526-968X

Autores

Richard Possemato, Kevin Eggan, Benjamin J. Moeller, Rudolf Jaenisch, Laurie Jackson‐Grusby,

Tópico(s)

RNA Research and Splicing

Resumo

genesisVolume 32, Issue 2 p. 184-186 ArticleFree Access Flp recombinase regulated lacZ expression at the ROSA26 locus Richard Possemato, Richard Possemato Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorKevin Eggan, Kevin Eggan Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorBenjamin J. Moeller, Benjamin J. Moeller Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorRudolf Jaenisch, Rudolf Jaenisch Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorLaurie Jackson-Grusby, Corresponding Author Laurie Jackson-Grusby [email protected] Whitehead Institute for Biomedical Research, Cambridge, MassachusettsWhitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142Search for more papers by this author Richard Possemato, Richard Possemato Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorKevin Eggan, Kevin Eggan Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorBenjamin J. Moeller, Benjamin J. Moeller Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorRudolf Jaenisch, Rudolf Jaenisch Whitehead Institute for Biomedical Research, Cambridge, Massachusetts Massachusetts Institute of Technology, Cambridge, MassachusettsSearch for more papers by this authorLaurie Jackson-Grusby, Corresponding Author Laurie Jackson-Grusby [email protected] Whitehead Institute for Biomedical Research, Cambridge, MassachusettsWhitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142Search for more papers by this author First published: 13 February 2002 https://doi.org/10.1002/gene.10039Citations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. LITERATURE CITED Awatramani R, Soriano P, Mai JJ, Dymecki S. 2001. An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus. Nat Genet 29: 257– 259. Buchholz F, Angrand PO, Stewart AF. 1998. Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat Biotechnol 16: 657– 662. Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM III, Yanagimachi R, Jaenisch R. 2001. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc Natl Acad Sci U S A 98: 6209– 6214. Friedrich G, Soriano P. 1991. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5: 1513– 1523. Jat PS, Cepko CL, Mulligan RC, Sharp PA. 1986. Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Mol Cell Biol 6: 1204– 1217. 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Proc Natl Acad Sci U S A 85: 5166– 5170. Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain [letter]. Nat Genet 21: 70– 71. Tallquist MD, Soriano P. 2000. Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. genesis 26: 113– 115. Thomas KR, Capecchi MR. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51: 503– 512. Van Parijs L, Refaeli Y, Lord JD, Nelson BH, Abbas AK, Baltimore D. 1999. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 11: 281– 288. Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P. 1997. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A 94: 3789– 3794. Citing Literature Volume32, Issue2Special Issue: Conditional Alleles in MiceFebruary 2002Pages 184-186 ReferencesRelatedInformation

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