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The Free Cytoplasmic Fragments of Lymphoglandular Tissue (Lymphoglandular Bodies). A Preliminary Presentation

1968; Wiley; Volume: 5; Issue: 2 Linguagem: Inglês

10.1111/j.1600-0609.1968.tb01729.x

0036-553X

Nils Söderström,

Lymphatic Disorders and Treatments

Lymphoglandular bodies are well organized fragments of cytoplasm from different types of cells occurring in lymphoglandular – or lymphatic – tissue (lymph glands, tonsils, thymus, spleen, diffuse and ectopic lymphoglandular tissue). They are also seen in lymphomas. They are especially conspicuous in imprints and smears from needle biopsy specimens. They are quite specific for this type of tissue and in needle biopsy specimens they thus permit the distinction of lymphomas from malignant tumors of other origin and the recognition of ectopic lymphoglandular metaplasia. Lymphoglandular bodies are no artefacts, they are seen also in tissue sections, especially in the efferent sinuses but also in some regions of solid lymphoglandular parenchyma. They might thus be regarded as analogs to other corpuscular products of haemopoietic tissues (e.g. platelets), and may be released together with cells leaving the lymphoglandular tissue. They are very short‐lived, they are rare in the thoracic duct lymph and do not seem to reach circulating blood as distinct morphologic units. They may represent an important detail in the function of lymhoglandular tissue but main points in their natural history are still obscure.