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BIBTEX RIS

Leprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort

2009; Lippincott Williams & Wilkins; Volume: 23; Issue: 5 Linguagem: Inglês

10.1097/qad.0b013e3283291405

1473-5571

Vinicius Martins de Menezes, Anna Maria Sales, Ximena Illarramendi, Alice Miranda, Mariza Gonçalves Morgado, Maria Clara Gutierrez‐Galhardo, Euzenir Nunes Sarno, José Augusto da Costa Nery,

Hematological disorders and diagnostics

Several case reports have demonstrated that the immune reconstitution inflammatory syndrome induces reversal reaction in HIV and leprosy-coinfected patients. The present study describes 10 cases of immune reconstitution inflammatory-associated reversal reaction. The patients evolved satisfactorily despite presenting a more severe form of the disease and the fact that three required an additional use of corticoids. The present study, the largest case series published to date, demonstrates that leprosy reaction is a manifestation of immune reconstitution.